Shifting Patterns in Mental Illness

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Presentation transcript:

Shifting Patterns in Mental Illness Cell Volume 155, Issue 6, (December 2013) DOI: 10.1016/j.cell.2013.11.026 Copyright © 2013 Terms and Conditions

Shank3 overexpression leads to altered excitatory/inhibitory balance in neurons and mania-like behavior and seizures in mice. Image courtesy of H. Zoghbi. Cell 2013 155, DOI: (10.1016/j.cell.2013.11.026) Copyright © 2013 Terms and Conditions

Trace of the movements of mutant mice with severe inner-ear defects and increased locomotor activity. Image courtesy of J. Hébert. Cell 2013 155, DOI: (10.1016/j.cell.2013.11.026) Copyright © 2013 Terms and Conditions

Calcineurin knockout mice are unable to use representations of sequences of future and past behaviors to consolidate memories and plan future actions. Image courtesy of Z. Vessal. Cell 2013 155, DOI: (10.1016/j.cell.2013.11.026) Copyright © 2013 Terms and Conditions