A) The distribution of normally aerated (white circles), poorly aerated (grey circles), non-aerated (black rectangle) and consolidated (green rectangle)

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Presentation transcript:

a) The distribution of normally aerated (white circles), poorly aerated (grey circles), non-aerated (black rectangle) and consolidated (green rectangle) lung areas during acute respiratory distress syndrome while in the supine position during end-inspiratio... a) The distribution of normally aerated (white circles), poorly aerated (grey circles), non-aerated (black rectangle) and consolidated (green rectangle) lung areas during acute respiratory distress syndrome while in the supine position during end-inspiration and end-expiration. b) Barotrauma (alveolar rupture with air leaks) and volutrauma (overdistension in the normally aerated lung areas). c) Atelectrauma, i.e. shear stress in the poorly aerated lung areas close to the consolidated non-recruitable lung areas. Biotrauma (biochemical and biological response) results from volutrauma and/or atelectrauma with activation of pro-inflammatory mediators within the lungs and distant end organs. The red circle represents the heart. Claude Guérin Eur Respir Rev 2014;23:249-257 ©2014 by European Respiratory Society