Analysis of Pentamer interfaces.

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Presentation transcript:

Analysis of Pentamer interfaces. Analysis of Pentamer interfaces. Interfaces of Pentamer with gH, gL, UL128, UL130, and UL131A are colored in gray, green, magenta, yellow, and blue, respectively. The N-terminal extension in gL is colored bright green, whereas only D-I of gH is shown for clarity. Starting with the top right and going clockwise, boxed subpanels show details of the interactions at the subunit interfaces of UL130-UL131A, gL-UL130, gH-gL, gL-UL128, and UL128-UL130-UL131A, with key residues depicted as sticks. Disulfides are shown as black sticks, and polar contacts are shown as dashed black lines. For gH/gL, only the interface involving the double disulfide between the respective N termini is shown. Sumana Chandramouli et al. Sci. Immunol. 2017;2:eaan1457 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.