Illustration to highlight the design and analysis time frame (relative to the study start or index date) of different types of real-world evidence studies. Arrows.

Slides:



Advertisements
Similar presentations
Look what I did! date page began___________ Dr. Foxs signature and date: ________________ time:_____.
Advertisements

This is Not a Book About …. Author: Illustrator: Class: Date:
From: Pattern matching is assessed in retinotopic coordinates
The arm electrodes (A and B) are placed on the mid-arm, on the lateral aspect of the biceps, immediately below the V4 horizontal line. The arm electrodes.
Correlation between maximal workload as achieved during a physical exercise test (treadmill or bicycle; horizontal axis) and left superficial femoral artery.
Hypertensive mechanisms of fructose
What number is the arrow pointing at?
Masashi Maeda et al. Heart Asia 2013;5:7-14
(A) Image of a stent that was damaged withdrawing it back into a Guideliner V2 after failing to cross the lesion. (A) Image of a stent that was damaged.
(A) Illustration of the receiver operating characteristic (ROC) curve (discrimination) of the recalibrated model on the external validation set data. (A)
Demonstrating changes in brachial artery diameter, with FMD transient response following cuff deflation at 5 min (frame ∼1800) and sustained NMD response.
Bar chart of cardiac volumes and EF in the healthy individuals, HCM LVH− patients and HCM LVH+ patients. Blue bars show the indexed diastolic volumes (EDVI.
(A) Kaplan-Meier curve showing AF-free survival after a single procedure for patients grouped according to use of CT integration. (A) Kaplan-Meier curve.
Classification of left ventricular (LV) size by (A) LV internal diameter in diastole (LVIDD) according to LV end-diastolic volume index (LVEDVi), (B) LVIDD.
Metaregression showing the relationship between mortality and antiplatelet strategy. Metaregression showing the relationship between mortality and antiplatelet.
(A) 1-year mortality in relation to estimated glomerular filtration rate (eGFR), age (n=47 636) and presence of diabetes mellitus (n=47 624). (A) 1-year.
Comparison of CMR and echocardiography in aortic regurgitation.
Correlation of change in H2 concentration (△H2) haemodynamics or laboratory parameters. Correlation of change in H2 concentration (△H2) haemodynamics or.
Thing / Person:____________________ Dates:_________________
Kaplan-Meier curves showing the time in months to the first inappropriate shock from the start of remote monitoring in primary and secondary prevention.
Absolute ST segment elevation at the beginning of the primary percutaneous coronary intervention procedure (A), after guidewire passage (B), after thrombus.
The volume per centre plotted against clinical outcomes which included Hospital Anxiety and Depression Scale (HADS) score, exercise 150 min, smoking, body.
Distribution of relative percentage change ((post-AVR−pre-AVR)/pre-AVR) in the patients’ absolute pVO2 values between pre-AVR and post-AVR after 9 months.
A large thoracoabdominal aneurysm is being resected.
Inflammatory response and CD34+CD45− cell release following percutaneous coronary intervention (PCI). Inflammatory response and CD34+CD45− cell release.
Incidence of contrast-induced nephropathy in patients with CKD, normal kidney function and all patients. Incidence of contrast-induced nephropathy in patients.
UK paediatric cardiac surgery mortality rate by year for all cases and total number of procedures performed between 2000 and 2009/2010. UK paediatric cardiac.
Examples from gross anatomical pathology.
(A) Absolute and (B) change from baseline in 6 min walk distance over time for all patients and by Down syndrome status. (A) Absolute and (B) change from.
Cost of healthcare and sick leave before and after heart valve surgery (€). Cost of healthcare and sick leave before and after heart valve surgery (€).
Kaplan-Meier curve of cumulative percentage of cardiac mortality by peak flow rate category (adjusted HRs (95% CI) compared with ≥550 L/min: (
Titration activities from baseline up to 6 and 12 months follow-up in nurse-coordinated care (NCC) versus usual care patients. X-as: patients (percentage),
Screen shot of the MIA-IIc brachial analyser software recording the diameter of the brachial artery using B mode ultrasound, by identification of the lines.
Different behaviours between group 1 and group 2 patients of the mean and SD of Δ for low frequency (LF), high frequency (HF) and total power (TP) calculated.
ASCOT: randomised trial showing a decrease in cardiovascular mortality in patients treated with amlodipine/perindopril compared with atenolol/thiazide.
Comparison of the change in index of microcirculatory resistance (IMR) at each stage of the primary percutaneous coronary intervention (PPCI) for balloon.
Kaplan–Meier plots of 5 and 12-year all cause (A and C, respectively) and cardiovascular mortality (B and D, respectively) with number of participants.
(A) Absolute and B) change from baseline in 6 min walk distance over time for patients on bosentan monotherapy by Down syndrome status. (A) Absolute and.
Standard mean difference of change in creatinine between the intravenous (IV) versus oral (PO) arm. Standard mean difference of change in creatinine between.
Representative images of coronary angiography and fractional flow reserve (FFR) from a patient who showed no resting ECG abnormality. Representative images.
Examples of recordings in an Interventional Cardiologist's Activities in Daily Life (ICADLs). Examples of recordings in an Interventional Cardiologist's.
An ascending aorta so thin that the writing on a ruler can be read directly through the wall. An ascending aorta so thin that the writing on a ruler can.
Number of patients who would have benefitted from addition of ACE inhibitor (ACEi), beta blockers (BB) or optimal therapy (one or both of ACEi and BB)
Illustration of a trial design to help evaluate the clinical accuracy of a test of ischaemia. Illustration of a trial design to help evaluate the clinical.
Dimensions indexed to body surface area (AGA, appropriate birth weight for gestational age; SGA, small for gestational age; LVED, left ventricular end-diastolic;
The top device is the XE2, used in TITAN
(A) The ECG of a middle aged woman who was otherwise healthy but suffered a ventricular fibrillation cardiac arrest while receiving 20 mg daily of thioridazine.
Forest plot illustrating the risk ratio of any bleeding and GRADE assessment. AF, atrial fibrillation; DOAC, advent of direct oral anticoagulants; PCI,
Illustrative four-chamber (left) and parasternal long axis (right) echocardiographic image of a female aged 49 years with systolic displacement of anterior.
Effect of sacubitril/valsartan on the rate of heart failure (HF) hospitalisations as a time to first event analysis and as a recurrent event analysis of.
Risk for cardiovascular disease and all-cause death according to RHR: (A) as categorical variable (HR≥75 bpm vs HR
Calculating the overall accuracy in different samples using the V-plot
Use of evidence-based cardiac medications before, during and after hospitalisation for the index event in (A) overall ACS population and (B) patients with.
Countries and areas of the Western Pacific region included within the scope of this study. Taiwan does not have WHO Member State status but is within this.
Forest plot illustrating the risk ratio of major bleeding
The QT interval responses to different pacing rates in a patient in group I. The pacing rate was decreased from 110 to 50 beats/min and the QT interval.
Virtual histology intravascular ultrasound (IVUS) appearance: A still image of a virtual histology IVUS frame from the left anterior descending artery.
Forest plot illustrating the risk ratio of myocardial infarction
Forest plot illustrating risk ratio of stent thrombosis
Metaregression showing the relationship between bleeding and antiplatelet strategy. Metaregression showing the relationship between bleeding and antiplatelet.
Determinants of moderate Cardiovascular Health Index Score (achieving three or more risk factor targets), stratified by region conventions as in figure.
HR for mortality in ischemic heart disease.
Effect of sacubitril/valsartan on the rate of primary end point and component and all-cause mortality in patients randomised in the PARADIGM-HF trial according.
Kaplan-Meier curve of the primary outcome in patients prescribed ACE inhibitor (ACEI) and angiotensin receptor blocker (ARB). Kaplan-Meier curve of the.
HR for myocardial infarction.
(A) Kaplan-Meier estimates of MACCE in patients with a non-culprit MaxLCBI4mm ≥400 and MaxLCBI4mm
Comparison of heart failure admissions rates per annum (recorded hospital admissions/ population at risk) in western developed countries 1978 to.
NYHA before and after at least 30–60 days after TAVI
Kaplan-Meier curves showing the probability of symptom-free survival according to the rate of heart rate rise during exercise testing in (A) for the whole.
Change of LV filling pattern with exercise.
Presentation transcript:

Illustration to highlight the design and analysis time frame (relative to the study start or index date) of different types of real-world evidence studies. Arrows depict prospective or retrospective studies of various durations. Illustration to highlight the design and analysis time frame (relative to the study start or index date) of different types of real-world evidence studies. Arrows depict prospective or retrospective studies of various durations. A John Camm, and Keith A A Fox Open Heart 2018;5:e000788 ©2018 by British Cardiovascular Society