Pathway analysis of genes upregulated after RSV infection. Pathway analysis of genes upregulated after RSV infection. The top 130 genes identified by a literature search are organized on the basis of their predicted functions and subcellular locations. Top candidates are indicated by bold outlining, upregulated genes are red, and downregulated genes are green. Interactions between the top 16 upregulated genes and the top 5 downregulated genes are based on known interactions in the IPA knowledge base. Jacqueline U. McDonald et al. mSystems 2016; doi:10.1128/mSystems.00051-16