Edge-to-edge (Alfieri) mitral repair: results in diverse clinical settings Sunil K Bhudia, MD, Patrick M McCarthy, MD, Nicholas G Smedira, MD, Buu-Khanh.

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Edge-to-edge (Alfieri) mitral repair: results in diverse clinical settings Sunil K Bhudia, MD, Patrick M McCarthy, MD, Nicholas G Smedira, MD, Buu-Khanh Lam, MD, Jeevanantham Rajeswaran, MS, Eugene H Blackstone, MD The Annals of Thoracic Surgery Volume 77, Issue 5, Pages 1598-1606 (May 2004) DOI: 10.1016/j.athoracsur.2003.09.090

Fig 1 Evolution of mitral regurgitation (MR) after edge-to-edge mitral valve repair. Symbols represent grouped data according to percent of observations of grade of mitral regurgitation • = grade 0; ○ = 1+; □ = 2+; Δ = 3+; ♢ = 4+. Solid lines indicate predicted mean percentage of patients in each MR grade with time from longitudinal modeling. The Annals of Thoracic Surgery 2004 77, 1598-1606DOI: (10.1016/j.athoracsur.2003.09.090)

Fig 2 Patients with mitral regurgitation (MR) grades 3+ or 4+ after edge-to-edge repair in patients with ischemic cardiomyopathy, dilated cardiomyopathy, and degenerative mitral disease. Solid lines indicate predicted mean percentage of patients and dashed lines indicate 68% confidence limits from longitudinal model. • = ischemic; ○ = dilated; □ = degenerative. The Annals of Thoracic Surgery 2004 77, 1598-1606DOI: (10.1016/j.athoracsur.2003.09.090)

Fig 3 Predicted percentage of patients with grade 3+ or 4+ mitral regurgitation (MR) after edge-to-edge repair according to left ventricular reconstruction (solid line and •) or not (solid line and ○) among patients with preoperative ischemic mitral regurgitation. Dashed lines(broad = left ventricular reconstruction; narrow = non–left ventricular reconstruction) show 68% confidence limits. The Annals of Thoracic Surgery 2004 77, 1598-1606DOI: (10.1016/j.athoracsur.2003.09.090)

Fig 4 Freedom from death. The solid line shows predicted curve with 68% confidence limits in dashed line. Numbers in parentheses show patients at risk at 1, 3, and 4.5 years. The Annals of Thoracic Surgery 2004 77, 1598-1606DOI: (10.1016/j.athoracsur.2003.09.090)