48 clinically relevant GPCR receptors mapped using MYTH

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48 clinically relevant GPCR receptors mapped using MYTH 48 clinically relevant GPCR receptors mapped using MYTH GPCR interactome. Validated interactions between baits–preys and preys targeted by drugs are highlighted. Drug targets were downloaded from DrugBank, drugs sales and prescription numbers were obtained from Medscape (2015). Bait–prey interactions are based on the IID database (black edges), MYTH detection (red edges), and validation assays (thick red edges). Nodes are ordered and categorized by NAViGaTOR 3's GO Molecular Function categorizer. Square nodes correspond to GPCR baits, while circular nodes correspond to interacting prey partners. Kate Sokolina et al. Mol Syst Biol 2017;13:918 © as stated in the article, figure or figure legend