The impact of arterial cannulation strategy on operative outcomes in aortic surgery: Evidence from a comprehensive meta-analysis of comparative studies.

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Presentation transcript:

The impact of arterial cannulation strategy on operative outcomes in aortic surgery: Evidence from a comprehensive meta-analysis of comparative studies on 4476 patients Umberto Benedetto, MD, PhD, Shahzad G. Raja, MRCS, FRCS(C-Th), Mohamed Amrani, MD, PhD, John R. Pepper, MD, FRCS, Mohamed Zeinah, FRCS(C-Th), Euclide Tonelli, MD, Giuseppe Biondi-Zoccai, MD, Giacomo Frati, MD The Journal of Thoracic and Cardiovascular Surgery Volume 148, Issue 6, Pages 2936-2943.e4 (December 2014) DOI: 10.1016/j.jtcvs.2014.05.082 Copyright © 2014 Terms and Conditions

Figure 1 Flow chart depicting study selection for meta-analysis. CC, Central cannulation; PC, peripheral cannulation. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2936-2943.e4DOI: (10.1016/j.jtcvs.2014.05.082) Copyright © 2014 Terms and Conditions

Figure 2 Forest plot for in-hospital mortality (top) and PND (bottom). CC, Central cannulation; PC, peripheral cannulation; CI, confidence interval. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2936-2943.e4DOI: (10.1016/j.jtcvs.2014.05.082) Copyright © 2014 Terms and Conditions

Figure E1 Forest plot according to study quality for in-hospital mortality (top) and PND (bottom). CC, Central cannulation; PC, peripheral cannulation; CI, confidence interval. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2936-2943.e4DOI: (10.1016/j.jtcvs.2014.05.082) Copyright © 2014 Terms and Conditions

Figure E2 Forest plot according to aortic cause for in-hospital mortality (left) and PND (right). CC, Central cannulation; PC, peripheral cannulation; CI, confidence interval; TAAAD, type A aortic acute dissection; CP, peripheral cannulation. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2936-2943.e4DOI: (10.1016/j.jtcvs.2014.05.082) Copyright © 2014 Terms and Conditions

Figure E3 Forest plot according to central cannulation site for in-hospital mortality (left) and PND (right). CC, Central cannulation; PC, peripheral cannulation; CI, confidence interval. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2936-2943.e4DOI: (10.1016/j.jtcvs.2014.05.082) Copyright © 2014 Terms and Conditions

Figure E4 Forest plot according to cerebral protection strategy for in-hospital mortality (left) and PND (right). CC, Central cannulation; PC, peripheral cannulation; CI, confidence interval; PND, permanent neurologic deficit. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2936-2943.e4DOI: (10.1016/j.jtcvs.2014.05.082) Copyright © 2014 Terms and Conditions

Figure E5 Funnel plot for publication bias assessment for in-hospital mortality (top) and PND (bottom). PND, Permanent neurologic deficit; RR, risk ratio; SE, standard error. The Journal of Thoracic and Cardiovascular Surgery 2014 148, 2936-2943.e4DOI: (10.1016/j.jtcvs.2014.05.082) Copyright © 2014 Terms and Conditions