HIV-related nephropathy: A South African perspective

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HIV-related nephropathy: A South African perspective T.E. Gerntholtz, S.J.W. Goetsch, I. Katz  Kidney International  Volume 69, Issue 10, Pages 1885-1891 (May 2006) DOI: 10.1038/sj.ki.5000351 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Comparing HIV-positive with HIV-negative patients biopsied during the study period. HIVICK: immune complex deposition disease; other GN’s: other glomerulonephritides; HIVAN: collapsing nephropathy; IgAN: IgA nephropathy; PIGN: post-infectious glomerulonephritis; other: other (non-glomerulonephritic) renal disease; MP: mesangial proliferative glomerulonephritis; FSGS: focal glomerulosclerosis; and min change: minimal change. Kidney International 2006 69, 1885-1891DOI: (10.1038/sj.ki.5000351) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 2 Global mesangial hyperplasia, with eosinophilic deposits within the mesangial and paramesangial regions (see encircled tuft). Silver–methenamine stain, original magnification, × 1000 (oil-immersion). Kidney International 2006 69, 1885-1891DOI: (10.1038/sj.ki.5000351) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 3 Electron microscopy depicting electron-dense deposits within the mesangial and paramesangial regions (see black arrows). Kidney International 2006 69, 1885-1891DOI: (10.1038/sj.ki.5000351) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 4 Subepithelial eosinophilic deposits in relation to the glomerular basement membranes, with a ‘ball-in-cup’ reaction pattern (see encircled and enlarged tuft with capillary loop). Silver–methenamine stain, original magnification, × 1000 (oil-immersion). Kidney International 2006 69, 1885-1891DOI: (10.1038/sj.ki.5000351) Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 5 Electron microscopy depicting a subepithelial ‘ball-in-cup’ deposit (see black arrow). Kidney International 2006 69, 1885-1891DOI: (10.1038/sj.ki.5000351) Copyright © 2006 International Society of Nephrology Terms and Conditions