Paraffinoma and Carcinoid Tumorlet: A Hitherto Unreported Association Mimicking Lung Cancer Christian Casali, MD, Giulio Rossi, MD, PhD, Elena Siopis,

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Paraffinoma and Carcinoid Tumorlet: A Hitherto Unreported Association Mimicking Lung Cancer Christian Casali, MD, Giulio Rossi, MD, PhD, Elena Siopis, MD, Giuseppe Fontana, MD, Morandi Uliano, MD Journal of Thoracic Oncology Volume 2, Issue 11, Pages 1052-1053 (November 2007) DOI: 10.1097/JTO.0b013e318158ef01 Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 A, Computed tomographic scan (lung windows): heterogeneous and spiculated mass of 2.5 × 2.8 cm, with low attenuation value areas (−10 to15 HU) of the superior segment of inferior right lobe. B, Enhanced computed tomographic scan (soft tissue windows): low attenuation areas with fat-equivalent density inside the mass (−28 HU) and diffuse high-contrast enhancement of the nearby tissue (arterial phase,18 HU; venous phase, 25 HU). C and D. [18F]-fluoro-2-deoxy-D-glucose-positron emission tomographic scan: area of increased uptake of [18F]-fluoro-2-deoxy-D-glucose in the right lobe corresponding to the nodule seen on computed tomographic scan. Journal of Thoracic Oncology 2007 2, 1052-1053DOI: (10.1097/JTO.0b013e318158ef01) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 A, Lung paraffinoma showing accumulation of macrophages with clear intracytoplasmic droplets into the alveolar spaces, interstitial fibrosis with lymphoid aggregates, and a carcinoid tumorlet around a bronchiole completely destroyed by a reactive central scar (hematoxylin and eosin stain, original magnification ×75). B, Positive staining with chromogranin in the tumorlet (immunohistochemistry, original magnification ×80). Journal of Thoracic Oncology 2007 2, 1052-1053DOI: (10.1097/JTO.0b013e318158ef01) Copyright © 2007 International Association for the Study of Lung Cancer Terms and Conditions