Assessment of Lymph Node Ratio to Replace the pN Categories System of Classification of the TNM System in Esophageal Squamous Cell Carcinoma Yingjie.

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Assessment of Lymph Node Ratio to Replace the pN Categories System of Classification of the TNM System in Esophageal Squamous Cell Carcinoma Yingjie Shao, MD, Yiting Geng, MD, Wendong Gu, MD, Zhonghua Ning, MD, Jin Huang, MD, Honglei Pei, MD, Jingting Jiang, PhD Journal of Thoracic Oncology Volume 11, Issue 10, Pages 1774-1784 (October 2016) DOI: 10.1016/j.jtho.2016.06.019 Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 Kaplan–Meier survival curves for patients stratified on the basis of (A) the seventh edition of the American Joint Committee on Cancer (AJCC) N categories, (B) revised N categories based on the metastatic lymph nodes ratio, (C) seventh edition of the AJCC TNM staging system, and (D) modified staging system with the revised N categories based on the metastatic lymph nodes ratio. Journal of Thoracic Oncology 2016 11, 1774-1784DOI: (10.1016/j.jtho.2016.06.019) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 Effect of metastatic lymph nodes ratio on the survival of patients with esophageal squamous cell carcinoma in the (A) pN1 and (B) pN2 subgroups. Journal of Thoracic Oncology 2016 11, 1774-1784DOI: (10.1016/j.jtho.2016.06.019) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 3 Time-dependent receiver operating characteristic curves for the seventh edition of the American Joint Committee on Cancer TNM staging system and modified staging system with the revised N categories for (A) 3-year and (B) 5-year overall survival. Decision curve analyses of the seventh edition of the American Joint Committee on Cancer TNM staging system and modified staging system with the revised N categories for (C) 3-year and (D) 5-year overall survival. AUC, area under the curve; CI, confidence interval. Journal of Thoracic Oncology 2016 11, 1774-1784DOI: (10.1016/j.jtho.2016.06.019) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 4 Kaplan–Meier survival curves for patients with an inadequate lymphadenectomy (<12 examined lymph nodes) stratified on the basis of the (A) seventh edition of the American Joint Committee on Cancer (AJCC) N categories, (B) revised N categories based on the metastatic lymph nodes ratio, (C) seventh edition of the AJCC TNM staging system, and (D) modified staging system with the revised N categories based on the metastatic lymph nodes ratio. Journal of Thoracic Oncology 2016 11, 1774-1784DOI: (10.1016/j.jtho.2016.06.019) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

Figure 5 Time-dependent receiver operating characteristic curves for the seventh edition of the American Joint Committee on Cancer TNM staging system and modified staging system with an inadequate lymphadenectomy (<12 examined lymph nodes) for (A) 3-year and (B) 5-year overall survival. Decision curve analyses of the seventh American Joint Committee on Cancer TNM staging system and modified staging system with the revised N categories for (C) 3-year and (D) 5-year overall survival. AUC, area under the curve. Journal of Thoracic Oncology 2016 11, 1774-1784DOI: (10.1016/j.jtho.2016.06.019) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions