Patient-Reported Outcomes and Endoscopic Appearance of Ulcerative Colitis: A Systematic Review and Meta-analysis Neeraj Narula, Abdul-Aziz Alshahrani,

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Presentation transcript:

Patient-Reported Outcomes and Endoscopic Appearance of Ulcerative Colitis: A Systematic Review and Meta-analysis Neeraj Narula, Abdul-Aziz Alshahrani, Yuhong Yuan, Walter Reinisch, Jean-Frederic Colombel Clinical Gastroenterology and Hepatology Volume 17, Issue 3, Pages 411-418.e3 (February 2019) DOI: 10.1016/j.cgh.2018.06.015 Copyright © 2019 AGA Institute Terms and Conditions

Figure 1 Study flow diagram. Clinical Gastroenterology and Hepatology 2019 17, 411-418.e3DOI: (10.1016/j.cgh.2018.06.015) Copyright © 2019 AGA Institute Terms and Conditions

Figure 2 Forest plots of coupled sensitivity and specificity of rectal bleeding subscore = 0 for mucosal healing. Clinical Gastroenterology and Hepatology 2019 17, 411-418.e3DOI: (10.1016/j.cgh.2018.06.015) Copyright © 2019 AGA Institute Terms and Conditions

Figure 3 Forest plots of coupled sensitivity and specificity of stool frequency subscore = 0 for mucosal healing. Clinical Gastroenterology and Hepatology 2019 17, 411-418.e3DOI: (10.1016/j.cgh.2018.06.015) Copyright © 2019 AGA Institute Terms and Conditions

Figure 4 Forest plots of coupled sensitivity and specificity of combined rectal bleeding and stool frequency subscores = 0 for mucosal healing. Clinical Gastroenterology and Hepatology 2019 17, 411-418.e3DOI: (10.1016/j.cgh.2018.06.015) Copyright © 2019 AGA Institute Terms and Conditions

Figure 5 (A) Summary receiver operating characteristic plot of sensitivity and specificity of rectal bleeding subscore = 0. (B) Summary receiver operating characteristic plot of sensitivity and specificity of stool frequency subscore = 0. (C) Summary receiver operating characteristic plot of sensitivity and specificity of combined rectal bleeding and stool frequency subscores = 0. Each circle indicates an individual study and it is sized according to number of subjects. Dark square represents summary point. Inner ellipse indicates 95% confidence region and outer ellipse indicates 95% prediction region. HSROC, hierarchical summary receiver operating characteristic curve. Clinical Gastroenterology and Hepatology 2019 17, 411-418.e3DOI: (10.1016/j.cgh.2018.06.015) Copyright © 2019 AGA Institute Terms and Conditions