Performance metrics for triplicate analyses of a tryptic digest of the CPTAC yeast reference proteome on four LTQ-Orbitraps at three different sites in CPTAC Study 6. Performance metrics for triplicate analyses of a tryptic digest of the CPTAC yeast reference proteome on four LTQ-Orbitraps at three different sites in CPTAC Study 6. Instruments labeled @56, @86, and @65O are LTQ-Orbitraps; the instrument labeled @65P is an LTQ-XL-Orbitrap. a–f display metrics according to category; values for each of the three runs are represented by a symbol. Low values for peptide identifications for instrument LTQ- Orbitrap@86 (a) coincide with low metric values for peptide ion charge states (metric IS-3B; c) and dynamic sampling (metric DS-1A; d) (see text for discussion). pep, peptide; IDs, identifications; med., median; ID'd, identified; fract., fraction; num, number; FWHM, full width at half-maximum; inject., injection. Paul A. Rudnick et al. Mol Cell Proteomics 2010;9:225-241 © 2010 by The American Society for Biochemistry and Molecular Biology, Inc.