Janet Rossant, Patrick P.L. Tam Cell Stem Cell

Slides:

Advertisements

Similar presentations

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Advertisements

Distinct Self-Renewal and Differentiation Phases in the Niche of Infrequently Dividing Hair Follicle Stem Cells Ying V. Zhang, Janice Cheong, Nichita Ciapurin,

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells David J. Wong, Helen Liu, Todd W. Ridky, David Cassarino, Eran Segal, Howard.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.

The Transcriptional and Functional Properties of Mouse Epiblast Stem Cells Resemble the Anterior Primitive Streak Yoji Kojima, Keren Kaufman-Francis, Joshua.

Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Kevin G. Chen, Barbara S. Mallon, Ronald D.G. McKay, Pamela G. Robey

Illuminating the Properties of Prostate Luminal Progenitors

Stress Can Be a Good Thing for Blood Formation

Cancer: Inappropriate Expression of Stem Cell Programs?

Human Naive Embryonic Stem Cells: How Full Is the Glass?

Janet Rossant, Patrick P.L. Tam Cell Stem Cell

Back to 2D Culture for Ground State of Intestinal Stem Cells

Kevin G. Chen, Barbara S. Mallon, Ronald D.G. McKay, Pamela G. Robey

FoxO: A New Addition to the ESC Cartel

Epithelial-Mesenchymal Transition and the Stem Cell Phenotype

Volume 1, Issue 1, Pages (June 2007)

Mending the Failing Heart with a Vascularized Cardiac Patch

Human Induced Pluripotent Stem Cells: Now Open to Discovery

Cell Cycle Rules Pluripotency

Why Myc? An Unexpected Ingredient in the Stem Cell Cocktail

A Path to Insulin Independence: “The End of the Beginning”

Surveillance for Secure Differentiation

Volume 16, Issue 6, Pages (June 2015)

Gerry P. Crossan, Juan I. Garaycoechea, Ketan J. Patel Cell Stem Cell

Anselme Perrier, Marc Peschanski Cell Stem Cell

Natalia J. Martinez, Richard I. Gregory Cell Stem Cell

Long Live Sox2: Sox2 Lasts a Lifetime

Regulating Cancer Stem Cells the miR Way

Wing Y. Chang, William L. Stanford Cell Stem Cell

Stem Cell Therapies in Clinical Trials: Progress and Challenges

Embryos, Camera, Laser, Action!

Stem Cells and Early Lineage Development

Human Induced Pluripotent Stem Cells: Now Open to Discovery

On the Origin of the Term “Stem Cell”

Why Myc? An Unexpected Ingredient in the Stem Cell Cocktail

MicroRNA Regulation of Stem Cell Fate

Recreating Pluripotency?

Tim Willinger, Richard A. Flavell Cell Stem Cell

Putting Two Heads Together to Build a Better Brain

Early Embryos Reprogram DNA Methylation in Two Steps

Chemical-Induced Naive Pluripotency

Volume 21, Issue 1, Pages (July 2011)

Loukia Yiangou, Alexander D.B. Ross, Kim Jee Goh, Ludovic Vallier

A Coated Sponge: Toward Neonatal Brain Repair

Pluripotent Stem Cells and Disease Modeling

Michael Hicks, April Pyle Cell Stem Cell

What Your Heart Doth Know

Dynamic Pluripotent Stem Cell States and Their Applications

Powering Reprogramming with Vitamin C

Mapping Cancer Origins

Copyright © 2013 Elsevier Inc. All rights reserved.

Regulating Autologous Adult Stem Cells: The FDA Steps Up

TGFβ and SMADs Talk to NANOG in Human Embryonic Stem Cells

Capturing Totipotent Stem Cells

The Plasticity of Aging: Insights from Long-Lived Mutants

Yoko Nakai-Futatsugi, Hitoshi Niwa Cell Stem Cell

Volume 22, Issue 4, Pages (April 2018)

Long Live Sox2: Sox2 Lasts a Lifetime

Regulating Autologous Adult Stem Cells: The FDA Steps Up

Zeki Beyhan, Amy E. Iager, Jose B. Cibelli Cell Stem Cell

Mesp1 at the Heart of Mesoderm Lineage Specification

Presentation transcript:

New Insights into Early Human Development: Lessons for Stem Cell Derivation and Differentiation Janet Rossant, Patrick P.L. Tam Cell Stem Cell Volume 20, Issue 1, Pages 18-28 (January 2017) DOI: 10.1016/j.stem.2016.12.004 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Species-Specific Schedule of Developmental Events and Differences in Tissue Patterning during Embryogenesis from Pre-implantation to the Onset of Gastrulation in Mouse and Human Embryos Only the embryonic region of the peri-implantation mouse embryo is shown for Stage TS8 and TS9. Staging of peri-implantation embryos: Mouse, Theiler (1989); Human, O’Rahilly and Muller (1987). Mouse Stage TS7: Reichert’s membrane (dark line between trophectoerm and endoderm); Mouse Stage TS7 and Human Stage 5a: epithelialization of the epiblast (dark apical line). Cell Stem Cell 2017 20, 18-28DOI: (10.1016/j.stem.2016.12.004) Copyright © 2017 Elsevier Inc. Terms and Conditions