Results of T4 Surgical Cases in the Japanese Lung Cancer Registry Study: Should Mediastinal Fat Tissue Invasion Really be Included in the T4 Category? 

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Results of T4 Surgical Cases in the Japanese Lung Cancer Registry Study: Should Mediastinal Fat Tissue Invasion Really be Included in the T4 Category?  Shun-ichi Watanabe, MD, Hisao Asamura, MD, Etsuo Miyaoka, PhD, Meinoshin Okumura, MD, Ichiro Yoshino, MD, Yoshitaka Fujii, MD, Yoichi Nakanishi, MD, Kenji Eguchi, MD, Masaki Mori, MD, Noriyoshi Sawabata, MD, Kohei Yokoi, MD  Journal of Thoracic Oncology  Volume 8, Issue 6, Pages 759-765 (June 2013) DOI: 10.1097/JTO.0b013e318290912d Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 A case of pT4 disease invading the mediastinal fat tissue. A, CT scan (lung field window) showing a left upper lobe tumor with visceral pleura involvement. B, CT scan (mediastinal window) showing the tumor invading the mediastinal fat tissue. C, Photograph of the formalin-fixed resected specimen. CT, computed tomography. Journal of Thoracic Oncology 2013 8, 759-765DOI: (10.1097/JTO.0b013e318290912d) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Survival curves of the 11,663 surgical cases in the Japanese Lung Cancer Registry Study grouped by pT factor International Union Against Cancer (IUCC)-Tumor Node Metastasis v. 7). Journal of Thoracic Oncology 2013 8, 759-765DOI: (10.1097/JTO.0b013e318290912d) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Survival curves of patients with pT4 disease grouped by reasons for being classified as T4. NS, not significant; PM, pulmonary metastasis. Journal of Thoracic Oncology 2013 8, 759-765DOI: (10.1097/JTO.0b013e318290912d) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 4 Survival curves of patients with pT4 disease grouped by pN status. Journal of Thoracic Oncology 2013 8, 759-765DOI: (10.1097/JTO.0b013e318290912d) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 5 Survival curves of patients with pT4 disease grouped by R status. NS, not significant. Journal of Thoracic Oncology 2013 8, 759-765DOI: (10.1097/JTO.0b013e318290912d) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 6 Survival curves of patients with pT4 disease grouped by age and nodal status. Journal of Thoracic Oncology 2013 8, 759-765DOI: (10.1097/JTO.0b013e318290912d) Copyright © 2013 International Association for the Study of Lung Cancer Terms and Conditions