Surgical Therapy for Bilateral Multiple Primary Lung Cancer

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Surgical Therapy for Bilateral Multiple Primary Lung Cancer Haitang Yang, MS, Yifeng Sun, PhD, Feng Yao, PhD, Keke Yu, MD, Haiyong Gu, PhD, Baohui Han, PhD, Heng Zhao, PhD The Annals of Thoracic Surgery Volume 101, Issue 3, Pages 1145-1152 (March 2016) DOI: 10.1016/j.athoracsur.2015.09.028 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Survival analysis based on histologic features and pathologic stage. (A) Survival comparisons based on histology in bilateral multiple primary lung cancer patients without N2 metastasis (n = 99), indicating that patients with bilateral adenocarcinoma (Ad-Ad) had a significantly better overall survival than patients with bilateral squamous cell carcinoma (Sq-Sq), but not between the Ad-Ad and different histologic types (DH) subgroups or between Sq-Sq and different histologic types subgroups. (B) Survival comparison according to the largest postoperative T (pT) stage (n = 101), showing that patients with largest T1 stage had significantly better overall survival than those with T2, and that there were no significant differences between those with T1 and T3 and those with T2 and T3. (C) Survival comparisons based on the highest postoperative N (pN) stage (n = 101), suggesting that patients with N0 had a significantly better overall survival than patients with N1 or N2, but there was not a significant difference between those with N1 and pN2. (D) Survival comparison according to the most advanced pTNM stage (n = 101), demonstrating that the more advanced the stage, the poorer the prognosis. The Annals of Thoracic Surgery 2016 101, 1145-1152DOI: (10.1016/j.athoracsur.2015.09.028) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions