Interferon beta-1a–induced morphea

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Interferon beta-1a–induced morphea Spencer A. Bezalel, BS, Bruce E. Strober, MD, PhD, Katalin Ferenczi, MD JAAD Case Reports Volume 1, Issue 1, Pages 15-17 (January 2015) DOI: 10.1016/j.jdcr.2014.10.002 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Depressed, indurated, bound-down hyperpigmented plaques involving anterior thighs (A) and right hip (B). JAAD Case Reports 2015 1, 15-17DOI: (10.1016/j.jdcr.2014.10.002) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Punch biopsy from the right thigh shows thickened collagen bundles extending into the subcutaneous fat, paucity of adnexal structures, and a deep reticular lymphocytic infiltrate (Hematoxylin-eosin stain; original magnification: ×4). B, Higher magnification image shows thickened collagen, lymphoplasmacytic infiltrate, and entrapment of the eccrine glands by collagen (original magnification: ×20). JAAD Case Reports 2015 1, 15-17DOI: (10.1016/j.jdcr.2014.10.002) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions