Multiplexed Molecular Profiling of Lung Cancer Using Pleural Effusion

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Multiplexed Molecular Profiling of Lung Cancer Using Pleural Effusion Hiroaki Akamatsu, MD, Yasuhiro Koh, MD, PhD, Hirotsugu Kenmotsu, MD, Tateaki Naito, MD, PhD, Masakuni Serizawa, PhD, Madoka Kimura, MD, Keita Mori, MSc, Hisao Imai, MD, PhD, Akira Ono, MD, PhD, Takehito Shukuya, MD, Tetsuhiko Taira, MD, PhD, Haruyasu Murakami, MD, PhD, Yasuhisa Ohde, MD, PhD, Masahiro Endo, MD, PhD, Takashi Nakajima, MD, PhD, Toshiaki Takahashi, MD, PhD, Nobuyuki Yamamoto, MD, PhD Journal of Thoracic Oncology Volume 9, Issue 7, Pages 1048-1052 (July 2014) DOI: 10.1097/JTO.0000000000000203 Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Flow chart of the patients analyzed in this study. Journal of Thoracic Oncology 2014 9, 1048-1052DOI: (10.1097/JTO.0000000000000203) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Proportion of samples with genetic abnormalities among whole population (N = 84), pathologically positive patients (N = 60), and pathologically negative patients (N = 17). In four patients, pathological diagnosis was not given. Journal of Thoracic Oncology 2014 9, 1048-1052DOI: (10.1097/JTO.0000000000000203) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Relative frequency of genetic abnormalities analyzed from 102 pleural effusion samples. Journal of Thoracic Oncology 2014 9, 1048-1052DOI: (10.1097/JTO.0000000000000203) Copyright © 2014 International Association for the Study of Lung Cancer Terms and Conditions