Association Between Disease-Specific Quality of Life and Magnetic Resonance Imaging Outcomes in a Clinical Trial of Prolotherapy for Knee Osteoarthritis

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Association Between Disease-Specific Quality of Life and Magnetic Resonance Imaging Outcomes in a Clinical Trial of Prolotherapy for Knee Osteoarthritis David Rabago, MD, Richard Kijowski, MD, Michael Woods, MD, Jeffrey J. Patterson, DO, Marlon Mundt, PhD, Aleksandra Zgierska, MD, PhD, Jessica Grettie, BS, John Lyftogt, MD, Luke Fortney, MD Archives of Physical Medicine and Rehabilitation Volume 94, Issue 11, Pages 2075-2082 (November 2013) DOI: 10.1016/j.apmr.2013.06.025 Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 1 Screening, enrollment, and randomization. Archives of Physical Medicine and Rehabilitation 2013 94, 2075-2082DOI: (10.1016/j.apmr.2013.06.025) Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 2 Among control participants, data show no correlation between change in CV and change in the WOMAC-based pain subscale score over 52 weeks (y=−0.0118x+0.1915, R²=.001), where y is the equation of the regression line and R² is the percent variation explained by the data. Archives of Physical Medicine and Rehabilitation 2013 94, 2075-2082DOI: (10.1016/j.apmr.2013.06.025) Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 3 Among prolotherapy participants, data show a correlation between change in CV and change in the WOMAC-based pain subscale score over 52 weeks (y=0.1338x+0.7236, R²=.1895), where y is the equation of the regression line and R² is the percent variation explained by the data. Archives of Physical Medicine and Rehabilitation 2013 94, 2075-2082DOI: (10.1016/j.apmr.2013.06.025) Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions