Volume 78, Issue 12, Pages (December 2010)

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Volume 78, Issue 12, Pages 1275-1280 (December 2010) Serum levels of matrix metalloproteinase-10 are associated with the severity of atherosclerosis in patients with chronic kidney disease Blai Coll, Jose A. Rodríguez, Lourdes Craver, Josune Orbe, Montserrat Martínez-Alonso, Alberto Ortiz, Javier Díez, Oscar Beloqui, Merce Borras, Jose M. Valdivielso, Elvira Fernández, José A. Páramo Kidney International Volume 78, Issue 12, Pages 1275-1280 (December 2010) DOI: 10.1038/ki.2010.329 Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure 1 Association between carotid intima-media thickness (cIMT) and proteolytic markers in the study population. Significant correlations between cIMT and concentration of matrix metalloproteinase (MMP)-10 (a) and tissue inhibitor of metalloproteinases type 1 (TIMP-1) (b) in patients under dialysis and chronic kidney disease (CKD) I–III, respectively. Kidney International 2010 78, 1275-1280DOI: (10.1038/ki.2010.329) Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure 2 Distribution of matrix metalloproteinase (MMP)-10 and MMP-8 in patients under dialysis according to the number of carotid plaques. *Analysis of variance, P-value=0.003 for MMP-10 and 0.001 for MMP-8. **Post hoc analyses of Bonferroni; P<0.05 between no plaque and the other groups. †Post hoc analyses of Bonferroni; P<0.05 between more than two plaques and the other groups. Kidney International 2010 78, 1275-1280DOI: (10.1038/ki.2010.329) Copyright © 2010 International Society of Nephrology Terms and Conditions