The glomerular filter: Biologic and genetic complexity

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The glomerular filter: Biologic and genetic complexity S.V. Dandapani, M.R. Pollak Kidney International Volume 70, Issue 6, Pages 980-982 (September 2006) DOI: 10.1038/sj.ki.5001801 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Laminin α5β2γ1 heterotrimer (also known as LM-521), the form present in the developed glomerular basement membrane. Mutations in the LAMB2 gene encoding the laminin β2 chain cause Pierson syndrome and congenital nephrotic syndrome. Adapted from Developmental Dynamics 2000; 218: 218–234 with permission from Wiley-Liss, Inc., a subsidiary of John Wiley & Sons, Inc. Kidney International 2006 70, 980-982DOI: (10.1038/sj.ki.5001801) Copyright © 2006 International Society of Nephrology Terms and Conditions