Volume 144, Issue 3, Pages (September 2013)

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Volume 144, Issue 3, Pages 896-902 (September 2013) CPAP Improves Endothelial Function in Patients With Minimally Symptomatic OSA Malcolm Kohler, MD, Sonya Craig, Justin C.T. Pepperell, MD, Debby Nicoll, PhD, Daniel J. Bratton, MSc, Andrew J. Nunn, MSc, Paul Leeson, PhD, John R. Stradling, MD CHEST Volume 144, Issue 3, Pages 896-902 (September 2013) DOI: 10.1378/chest.13-0179 Copyright © 2013 The American College of Chest Physicians Terms and Conditions

Figure 1 Consort diagram. FMD = flow-mediated dilatation; PWA = pulse wave analysis. CHEST 2013 144, 896-902DOI: (10.1378/chest.13-0179) Copyright © 2013 The American College of Chest Physicians Terms and Conditions

Figure 2 Forest plot showing a significant treatment effect of CPAP on endothelial function, assessed by FMD of the brachial artery, compared with standard care. There was no significant treatment effect of CPAP on arterial stiffness, assessed by augmentation index, compared with standard care. See Figure 1 legend for expansion of abbreviation. CHEST 2013 144, 896-902DOI: (10.1378/chest.13-0179) Copyright © 2013 The American College of Chest Physicians Terms and Conditions

Figure 3 Forest plot showing no statistically significant difference in the treatment effect on augmentation index in patients using CPAP < 4 h/night compared with those using it ≥ 4 h/night. The dashed line represents the overall treatment effect. CHEST 2013 144, 896-902DOI: (10.1378/chest.13-0179) Copyright © 2013 The American College of Chest Physicians Terms and Conditions

Figure 4 Forest plot showing a statistically significant difference in the treatment effect on FMD of the brachial artery in patients using CPAP < 4 h/night compared with those using it ≥ 4 h/night. The dashed line represents the overall treatment effect. See Figure 1 legend for expansion of abbreviation. CHEST 2013 144, 896-902DOI: (10.1378/chest.13-0179) Copyright © 2013 The American College of Chest Physicians Terms and Conditions