Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery  Torsten Doenst, MD, PhD,

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Presentation transcript:

Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery  Torsten Doenst, MD, PhD, Duminda Wijeysundera, MD, Keyvan Karkouti, MD, Christoph Zechner, MD, Manjula Maganti, MSc, Vivek Rao, MD, PhD, Michael A. Borger, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 130, Issue 4, Pages 1144.e1-1144.e8 (October 2005) DOI: 10.1016/j.jtcvs.2005.05.049 Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Peak glucose levels during cardiopulmonary bypass (CPB) and operative mortality in diabetic (n = 1579) and nondiabetic (n = 4701) patients operated on at our institution between January 1999 and December 2001. The numbers at the top of the columns indicate the percentage of patients with peak glucose levels in the respective range. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 1144.e1-1144.e8DOI: (10.1016/j.jtcvs.2005.05.049) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Highest serum glucose level during cardiopulmonary bypass (CPB) as a function of the duration of cardiopulmonary bypass in nondiabetic patients (n = 6280; Spearman correlation coefficient, r = 0.43). Note that 25 mmol/L (450 mg/dL) is the highest value the glucose analyzer displays. Thus a value of 25 mmol/L might reflect an even higher glucose level. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 1144.e1-1144.e8DOI: (10.1016/j.jtcvs.2005.05.049) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions