Trajectories and Predictors of Symptom Occurrence, Severity, and Distress in Prostate Cancer Patients Undergoing Radiation Therapy Katie Knapp, RN, MS,

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Presentation transcript:

Trajectories and Predictors of Symptom Occurrence, Severity, and Distress in Prostate Cancer Patients Undergoing Radiation Therapy Katie Knapp, RN, MS, Bruce Cooper, PhD, Theresa Koetters, RN, MS, Janine Cataldo, RN, PhD, Anand Dhruva, MD, Steven M. Paul, PhD, Claudia West, RN, MS, Bradley E. Aouizerat, PhD, MAS, Christine Miaskowski, RN, PhD, FAAN Journal of Pain and Symptom Management Volume 44, Issue 4, Pages 486-507 (October 2012) DOI: 10.1016/j.jpainsymman.2011.10.020 Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Observed (open circles) and predicted (filled circles) trajectories for the probability of occurrence of problems with a) urination, b) pain, c) lack of energy, d) feeling drowsy, e) difficulty sleeping, and f) diarrhea across the 25 weeks of the study. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Observed (open circles) and predicted (filled circles) trajectories for the probability of occurrence of problems with urination, across the 25 weeks of the study, in a) whites compared with b) nonwhites and in patients who d) did and c) did not report pain at the initiation of radiation therapy. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 3 Observed (open symbols) and predicted (filled symbols) trajectories for the probability of severity ratings for problems with a) urination, b) pain, c) lack of energy, d) feeling drowsy, e) difficulty sleeping, and f) diarrhea across the 25 weeks of the study. Severity ratings are plotted as none vs. slight to very severe and none/slight vs. moderate to very severe. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 4 Observed (open symbols) and predicted (filled symbols) trajectories for the probability of severity ratings for problems with urination, across the 25 weeks of the study, in patients who b) did and a) did not report pain at the initiation of radiation therapy. Severity ratings are plotted as none vs. slight to very severe and none/slight vs. moderate to very severe. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 5 Observed (open symbols) and predicted (filled symbols) trajectories for the probability of distress ratings for problems with a) urination, b) pain, c) lack of energy, d) feeling drowsy, e) difficulty sleeping, and f) diarrhea across the 25 weeks of the study. Distress ratings are plotted as did not have vs. not at all to very severe, did not have/not at all vs. mild to very severe, did not have to mild vs. moderate to very severe, and did not have to moderate vs. severe/very severe. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 6 Observed (open symbols) and predicted (filled symbols) trajectories for the probability of distress ratings for problems with urination, across the 25 weeks of the study, in patients who b) did and a) did not report pain at the initiation of radiation therapy. Distress ratings are plotted as did not have vs. not at all to very severe, did not have/not at all vs. mild to very severe, did not have to mild vs. moderate to very severe, and did not have to moderate vs. severe/very severe. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 7 Observed (open circles) and predicted (filled circles) trajectories for the probability of occurrence of lack of energy, across the 25 weeks of the study, in patients who b) were and a) were not on hormonal therapy and in patients who d) did and c) did not report pain at the initiation of radiation therapy. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 8 Observed (open symbols) and predicted (filled symbols) trajectories for the probability of severity ratings for lack of energy, across the 25 weeks of the study, in patients who b) did and a) did not report pain at the initiation of radiation therapy. Severity ratings are plotted as none vs. slight to very severe and none/slight vs. moderate to very severe. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 9 Observed (open symbols) and predicted (filled symbols) trajectories for the probability of distress ratings for lack of energy, across the 25 weeks of the study, in patients who b) were and a) were not on hormonal therapy and in patients who d) did and c) did not report pain at the initiation of radiation therapy. Distress ratings are plotted as did not have vs. not at all to very severe, did not have/not at all vs. mild to very severe, did not have to mild vs. moderate to very severe, and did not have to moderate vs. severe/very severe. Journal of Pain and Symptom Management 2012 44, 486-507DOI: (10.1016/j.jpainsymman.2011.10.020) Copyright © 2012 U.S. Cancer Pain Relief Committee Terms and Conditions