Clinical and radiobiological evaluation of a method for planning target volume generation dependent on organ-at-risk exclusions in magnetic resonance imaging- based prostate radiotherapy  Brian Ruiz, Yuanming Feng  Physics and Imaging in Radiation Oncology  Volume 8, Pages 51-56 (October 2018) DOI: 10.1016/j.phro.2018.11.007 Copyright © 2018 The Authors Terms and Conditions

Fig. 1 Axial, coronal, and sagittal view comparing conventional expansions (isotropic 8 mm, except 5 mm posterior) to the MRI-based delineation and expansion method. The extent of expansion into the bladder is less pronounced and expansion into the rectum is comparable to conventional expansions for this one representative case. PTV expansion into the rectum is variable depending on patient anatomy. Physics and Imaging in Radiation Oncology 2018 8, 51-56DOI: (10.1016/j.phro.2018.11.007) Copyright © 2018 The Authors Terms and Conditions

Fig. 2 (Left) DVH of PTV comparison for plan optimized with MRI-delineated prostate and conventional expansion methods (isotropic 8 mm, except 5 mm posterior) showing under-dosing of the conventional CT-expanded PTV. (Right) DVH of PTV comparison for plan optimized with MRI-based delineation and expansion method showing comparable coverage to conventional CT-expanded PTV. Physics and Imaging in Radiation Oncology 2018 8, 51-56DOI: (10.1016/j.phro.2018.11.007) Copyright © 2018 The Authors Terms and Conditions