Bone structural changes in osteoarthritis as a result of mechanoregulated bone adaptation: a modeling approach L.G.E. Cox, B. van Rietbergen, C.C. van.

Slides:

Advertisements

Similar presentations

Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.

Advertisements

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy P.T. Paradowski, L.S. Lohmander,

Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study

The importance of dose in land-based supervised exercise for people with hip osteoarthritis. A systematic review and meta-analysis T. Moseng, H. Dagfinrud,

Corrigendum to ‘The importance of dose in land-based supervised exercise for people with hip osteoarthritis. A systematic review and meta-analysis’ [Osteoarthritis.

The independent and combined effects of intensive weight loss and exercise training on bone mineral density in overweight and obese older adults with.

Mesenchymal stromal cells for cartilage repair in osteoarthritis

Short-term placebo response in trials of patients with symptomatic osteoarthritis: differences between hip and knee S. Reiter-Niesert, M. Boers, J. Detert

Association of knee and ankle osteoarthritis with physical performance

P.T. Paradowski, L.S. Lohmander, M. Englund

The epidemiology and impact of pain in osteoarthritis

P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung

Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis V. Silverwood, M. Blagojevic-Bucknall,

Osteoarthritis pain mechanisms: basic studies in animal models

B.J. Ahern, J. Parvizi, R. Boston, T.P. Schaer

Is a high tibial osteotomy (HTO) superior to non-surgical treatment in patients with varus malaligned medial knee osteoarthritis (OA)? A propensity matched.

B.J. Ahern, J. Parvizi, R. Boston, T.P. Schaer

Osteoarthritis as a disease of mechanics

Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials M. Fransen, S.

P.T. Paradowski, L.S. Lohmander, M. Englund

Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role.

Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives Y. Henrotin Osteoarthritis and Cartilage

Automatic cartilage segmentation and measurement for diagnosis of OA using 3D box and Gaussian filters X. Cui, S. Li, M. Yu, H. Kim, K.-S. Kwack, B.-H.

Cross-cultural adaptation and implementation of Good Life with osteoarthritis in Denmark (GLA:D™): group education and exercise for hip and knee osteoarthritis.

The interaction between weight and family history of total knee replacement with knee cartilage: a 10-year prospective study F. Pan, L. Blizzard, J.

Osteoarthritis pain mechanisms: basic studies in animal models

S.M. Hosseini, M.B. Veldink, K. Ito, C.C. van Donkelaar

Osteoarthritis year 2013 in review: genetics and genomics

Time to be positive about negative data?

J. Avouac, M.D., L. Gossec, M.D., M. Dougados, M.D.

E. Losina, S. A. Burbine, L. G. Suter, D. J. Hunter, D. H. Solomon, M

Stem cell therapy for human cartilage defects: a systematic review

S. Sonne-Holm, M.D., Dr. Sci., S. Jacobsen, M.D.

N.D. Miljkovic, M.D., Ph.D., G.M. Cooper, Ph.D., K.G. Marra, Ph.D.

N.R. Dostrovsky, T.E. Towheed, R.W. Hudson, T.P. Anastassiades

J. Ranstam Osteoarthritis and Cartilage

A numerical model to study mechanically induced initiation and progression of damage in articular cartilage S.M. Hosseini, W. Wilson, K. Ito, C.C. van.

The course of limitations in activities over 5 years in patients with knee and hip osteoarthritis with moderate functional limitations: risk factors for.

Osteoarthritis of the knee after meniscal resection: long term radiographic evaluation of disease progression P.T. Paradowski, L.S. Lohmander, M. Englund

M.Y. Chan, J.R. Center, J.A. Eisman, T.V. Nguyen

Utilization rates of hip arthroplasty in OECD countries

Scientific production and impact of national registers: the example of orthopaedic national registers P. Boyer, I. Boutron, P. Ravaud Osteoarthritis.

Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis M. Blagojevic, C. Jinks, A. Jeffery, K.P.

A graphic user interface for the evaluation of knee osteoarthritis (GEKO): an open- source tool for histological grading H.E. Kloefkorn, B.Y. Jacobs,

Who should have a joint replacement? A plea for more ‘phronesis’

Cartilage adaptation after anterior cruciate ligament injury and reconstruction: implications for clinical management and research? A systematic review.

Hip strengthening reduces symptoms but not knee load in people with medial knee osteoarthritis and varus malalignment: a randomised controlled trial

Z. Huang, T. Stabler, F. Pei, V. Kraus Osteoarthritis and Cartilage

I.C. Olsen, T.K. Kvien, T. Uhlig Osteoarthritis and Cartilage

D.J. Hunter Osteoarthritis and Cartilage

Evidence for bone mineral density and bone resorption in middle and elderly women with knee osteoarthritis in Shanghai: a cross sectional study Q. Xiaofeng

The association between hip bone marrow lesions and bone mineral density: a cross- sectional and longitudinal population-based study H. Ahedi, D. Aitken,

S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang

Limited effects of exercises in people with hand osteoarthritis: results from a randomized controlled trial N. Østerås, K.B. Hagen, M. Grotle, A.-L.

Instruments to assess physical activity in patients with osteoarthritis of the hip or knee: a systematic review of measurement properties C.B. Terwee,

C. Ratzlaff, M. Koehoorn, J. Cibere, J. Kopec

Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA- Quest): a psychometric study L. Busija, R. Buchbinder, R.H. Osborne Osteoarthritis.

N. Frey, T. Hügle, S.S. Jick, C.R. Meier, J. Spoendlin

Osteoarthritis year 2012 in review: biology

Alterations to the subchondral bone architecture during osteoarthritis: bone adaptation vs endochondral bone formation L.G.E. Cox, C.C. van Donkelaar,

Osteoarthritis year in review 2015: biology

Location-specific hip joint space width for progression of hip osteoarthritis – Data from the Osteoarthritis Initiative C. Ratzlaff, C. Van Wyngaarden,

Coll2-1, Coll2-1NO2 and myeloperoxidase serum levels in erosive and non-erosive osteoarthritis of the hands L. Punzi, R. Ramonda, M. Deberg, P. Frallonardo,

Systematic review of the impact of osteoarthritis on health outcomes for comorbid disease in older people L. Parkinson, D.L. Waters, L. Franck Osteoarthritis.

D.T. Felson Osteoarthritis and Cartilage

Longitudinal assessment of femoral knee cartilage quality using contrast enhanced MRI (dGEMRIC) in patients with anterior cruciate ligament injury – comparison.

Efficacy of rehabilitation programs for improving muscle strength in people with hip or knee osteoarthritis: a systematic review with meta-analysis A.

Osteoarthritis year in review 2016: mechanics

M. Doherty, P. Dieppe Osteoarthritis and Cartilage

General Information Osteoarthritis and Cartilage

Presentation transcript:

Bone structural changes in osteoarthritis as a result of mechanoregulated bone adaptation: a modeling approach L.G.E. Cox, B. van Rietbergen, C.C. van Donkelaar, K. Ito Osteoarthritis and Cartilage Volume 19, Issue 6, Pages 676-682 (June 2011) DOI: 10.1016/j.joca.2011.02.007 Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 The different loading conditions: (a) normal, (b) obesity, strenuous exercise, (c) malalignment, ACL injury, partial meniscectomy. Osteoarthritis and Cartilage 2011 19, 676-682DOI: (10.1016/j.joca.2011.02.007) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Simulated bone structures for different conditions: (a) normal, (b) obesity, strenuous exercise, (c) ACL injury, partial meniscectomy, malalignment, (d) reduced mineralization, (e) osteopetrosis. Osteoarthritis and Cartilage 2011 19, 676-682DOI: (10.1016/j.joca.2011.02.007) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Average SED in the bone during remodeling after changing the model parameters to simulate conditions associated with OA. Osteoarthritis and Cartilage 2011 19, 676-682DOI: (10.1016/j.joca.2011.02.007) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Apparent bone stiffness prior to and after the onset of different conditions, and after remodeling. Model parameters. Osteoarthritis and Cartilage 2011 19, 676-682DOI: (10.1016/j.joca.2011.02.007) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions