Magnetic resonance imaging in osteoarthritis: which method best reflects synovial membrane inflammation? D. Loeuille, A.-C. Rat, J.-C. Goebel, J. Champigneulle,

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Magnetic resonance imaging in osteoarthritis: which method best reflects synovial membrane inflammation? D. Loeuille, A.-C. Rat, J.-C. Goebel, J. Champigneulle, A. Blum, P. Netter, P. Gillet, I. Chary-Valckenaere Osteoarthritis and Cartilage Volume 17, Issue 9, Pages 1186-1192 (September 2009) DOI: 10.1016/j.joca.2009.03.006 Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 The two slices chosen for the MRI synovitis score corresponds to the first and the last axial post-injection T1-weighted slices in which the patella was still visible. SM inflammation was graded according to thickening severity in five ROI (1–5). The MRI synovitis score varied between 0 and 15. 254×190mm (72×72DPI). Osteoarthritis and Cartilage 2009 17, 1186-1192DOI: (10.1016/j.joca.2009.03.006) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 On axial post-injection T1-weighted slices (B), SM with a threshold of enhancement 45% was outlined (C) and the speed of enhancement was calculated for each voxel and categorized as: low (blue colour) intermediate (green colour), or high speed of enhancement (red colour) 254×190mm (72×72DPI (D)). Osteoarthritis and Cartilage 2009 17, 1186-1192DOI: (10.1016/j.joca.2009.03.006) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Only axial post-injection T1-weighted slices in which the patella was visualized were selected for volume analysis (A, B). On each slice, SM with a threshold of enhancement 45% was outlined and the SMV calculated (C). Finally the SMV was assessed according to its speed of enhancement and categorized as: low (blue colour), intermediate (green colour) or high speed of enhancement (red colour) (D). 254×190mm (72×72DPI). Osteoarthritis and Cartilage 2009 17, 1186-1192DOI: (10.1016/j.joca.2009.03.006) Copyright © 2009 Osteoarthritis Research Society International Terms and Conditions