Figure 1. Mean log10 cfu/mL versus time profile for each individual drug at 4× MIC against the four VRE ... Figure 1. Mean log<sub>10</sub> cfu/mL versus time profile for each individual drug at 4× MIC against the four VRE (a–d) and E. faecalis strain (e). Curves represent average concentrations for triplicate experiments. Each antibiotic is illustrated as follows: ceftriaxone, dashed line with open diamonds; daptomycin, dashed line with open crosses; gentamicin, dashed line with open circles; linezolid, dashed line with open triangles; rifampicin, dashed line with open squares; and oritavancin, dashed line with open stars. The growth control strain is illustrated by a solid line with crosses. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) J Antimicrob Chemother, Volume 74, Issue 5, 08 February 2019, Pages 1300–1305, https://doi.org/10.1093/jac/dkz010 The content of this slide may be subject to copyright: please see the slide notes for details.
Figure 2. Mean log10 cfu/mL versus time profile for each individual drug and combination at ¼× MIC against ... Figure 2. Mean log<sub>10</sub> cfu/mL versus time profile for each individual drug and combination at ¼× MIC against the four VRE (a–d) and E. faecalis strain (e). Curves represent average concentrations for triplicate experiments. Each antibiotic alone is illustrated as follows: ceftriaxone, dashed line with open diamonds; daptomycin, dashed line with open crosses; gentamicin, dashed line with open circles; linezolid, dashed line with open triangles; rifampicin, dashed line with open squares; and oritavancin, dashed line with open stars. Each antibiotic in combination with oritavancin is illustrated as follows: ceftriaxone, solid line with filled diamonds; daptomycin, solid line with filled crosses; gentamicin, solid line with filled circles; linezolid, solid line with filled triangles; rifampicin, solid line with filled squares; and oritavancin, solid line with filled stars. The growth control strain is illustrated by a solid line with crosses. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) J Antimicrob Chemother, Volume 74, Issue 5, 08 February 2019, Pages 1300–1305, https://doi.org/10.1093/jac/dkz010 The content of this slide may be subject to copyright: please see the slide notes for details.