Effects of perfusion mode on regional and global organ blood flow in a neonatal piglet model  Akif Ündar, PhD, Takafumi Masai, MD, Shuang-Qiang Yang,

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Presentation transcript:

Effects of perfusion mode on regional and global organ blood flow in a neonatal piglet model  Akif Ündar, PhD, Takafumi Masai, MD, Shuang-Qiang Yang, MD, Jan Goddard-Finegold, MD, O.H Frazier, MD, Charles D Fraser, MD  The Annals of Thoracic Surgery  Volume 68, Issue 4, Pages 1336-1342 (October 1999) DOI: 10.1016/S0003-4975(99)00913-3

Fig 1 Femoral artery pressure, pre-cannula extracorporeal circuit pressure, and pump flow during pulsatile cardiopulmonary bypass in a neonatal piglet. The Annals of Thoracic Surgery 1999 68, 1336-1342DOI: (10.1016/S0003-4975(99)00913-3)

Fig 2 Femoral artery pressure, pre-cannula extracorporeal circuit pressure, and pump flow during non-pulsatile cardiopulmonary bypass in a neonatal piglet. The Annals of Thoracic Surgery 1999 68, 1336-1342DOI: (10.1016/S0003-4975(99)00913-3)

Fig 3 Global cerebral blood flow during pulsatile versus non-pulsatile perfusion (mean ± SEM). ∗p < 0.05 pulsatile versus non-pulsatile groups; †p < 0.05 versus pre-CPB within pulsatile group; ‡p < 0.05 versus pre-CPB within non-pulsatile group. (CPB = cardiopulmonary bypass; DHCA = deep hypothermic circulatory arrest; NP = non-pulsatile; P = pulsatile). The Annals of Thoracic Surgery 1999 68, 1336-1342DOI: (10.1016/S0003-4975(99)00913-3)

Fig 4 Renal blood flow during pulsatile versus non-pulsatile perfusion (mean ± SEM). ∗p < 0.05 pulsatile versus non-pulsatile groups; †p < 0.01 versus pre-CPB within pulsatile group ‡p < 0.01 versus pre-CPB within non-pulsatile group. (CPB = cardiopulmonary bypass; DHCA = deep hypothermic circulatory arrest; NP = non-pulsatile; P = pulsatile). The Annals of Thoracic Surgery 1999 68, 1336-1342DOI: (10.1016/S0003-4975(99)00913-3)

Fig 5 Myocardial blood flow during pulsatile versus non-pulsatile perfusion (mean ± SEM). ∗p < 0.05 Pulsatile versus non-pulsatile groups; †p < 0.05 versus pre-CPB within pulsatile group; ‡p < 0.05 versus pre-CPB within non-pulsatile group. (CPB = cardiopulmonary bypass; DHCA = deep hypothermic circulatory arrest; NP = non-pulsatile; P = pulsatile). The Annals of Thoracic Surgery 1999 68, 1336-1342DOI: (10.1016/S0003-4975(99)00913-3)