Isotonic crystalloid solutions: a structured review of the literature

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Isotonic crystalloid solutions: a structured review of the literature D. Orbegozo Cortés, A. Rayo Bonor, J.L. Vincent  British Journal of Anaesthesia  Volume 112, Issue 6, Pages 968-981 (June 2014) DOI: 10.1093/bja/aeu047 Copyright © 2014 The Author(s) Terms and Conditions

Fig 1 Study selection tree. British Journal of Anaesthesia 2014 112, 968-981DOI: (10.1093/bja/aeu047) Copyright © 2014 The Author(s) Terms and Conditions

Fig 2 Forest plot of blood pH before (a) and after (b) fluid administration in studies comparing normal saline with Ringer’s lactate. British Journal of Anaesthesia 2014 112, 968-981DOI: (10.1093/bja/aeu047) Copyright © 2014 The Author(s) Terms and Conditions

Fig 3 Forest plot of lactate levels before (a) and after (b) fluid administration in studies comparing normal saline with Ringer’s lactate. British Journal of Anaesthesia 2014 112, 968-981DOI: (10.1093/bja/aeu047) Copyright © 2014 The Author(s) Terms and Conditions

Fig 4 Forest plot of blood loss volumes in studies comparing normal saline with Ringer’s lactate when considering all patients (a), patients with a low risk of bleeding (b), and patients with a high risk of bleeding (c). British Journal of Anaesthesia 2014 112, 968-981DOI: (10.1093/bja/aeu047) Copyright © 2014 The Author(s) Terms and Conditions

Fig 5 Forest plot of red blood cell transfusion volumes in studies comparing normal saline with Ringer’s lactate. British Journal of Anaesthesia 2014 112, 968-981DOI: (10.1093/bja/aeu047) Copyright © 2014 The Author(s) Terms and Conditions

Fig 6 Forest plot of first reported urinary output volume (a) or creatinine level (b) after the first 24 h of fluid administration in studies comparing normal saline with Ringer’s lactate. British Journal of Anaesthesia 2014 112, 968-981DOI: (10.1093/bja/aeu047) Copyright © 2014 The Author(s) Terms and Conditions