S. Pilge, D. Jordan, M. Kreuzer, E.F. Kochs, G. Schneider 

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Burst suppression-MAC and burst suppression-CP50 as measures of cerebral effects of anaesthetics  S. Pilge, D. Jordan, M. Kreuzer, E.F. Kochs, G. Schneider  British Journal of Anaesthesia  Volume 112, Issue 6, Pages 1067-1074 (June 2014) DOI: 10.1093/bja/aeu016 Copyright © 2014 The Author(s) Terms and Conditions

Fig 1 Screenshot of the EEG-based endpoint ‘silent second’ as recorded with an Aspect A 1000 BIS monitor. British Journal of Anaesthesia 2014 112, 1067-1074DOI: (10.1093/bja/aeu016) Copyright © 2014 The Author(s) Terms and Conditions

Fig 2 Determination of anaesthetic concentration for calculation of burst-suppression MAC (MACBS) and CP50BS with Dixon’s up-and-down technique. British Journal of Anaesthesia 2014 112, 1067-1074DOI: (10.1093/bja/aeu016) Copyright © 2014 The Author(s) Terms and Conditions

Fig 3 (a–c): Determination of cross-over pairs with Dixon’s up-and-down technique for the sevoflurane (a), isoflurane (b), and propofol (c) groups. Cross-over pairs are marked with (X). British Journal of Anaesthesia 2014 112, 1067-1074DOI: (10.1093/bja/aeu016) Copyright © 2014 The Author(s) Terms and Conditions

Fig 4 (a–c) Calculation of burst-suppression MAC (MACBS) and CP50BS with logistic regression for the sevoflurane (a), isoflurane (b), and propofol (c) groups. Blue dot: Burst suppression EEG; green ring: no burst suppression EEG. British Journal of Anaesthesia 2014 112, 1067-1074DOI: (10.1093/bja/aeu016) Copyright © 2014 The Author(s) Terms and Conditions