DIP–STR: A new marker for resolving unbalanced DNA mixtures

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Presentation transcript:

DIP–STR: A new marker for resolving unbalanced DNA mixtures D. Hall, V. Castella Forensic Science International: Genetics Supplement Series Volume 3, Issue 1, Pages e1-e2 (December 2011) DOI: 10.1016/j.fsigss.2011.08.065 Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 (A) A DIP–STR marker is composed of a DIP polymorphism (S/L alleles) linked to an STR polymorphism (e.g., 3/4 repeats). Arrows indicate PCR primers. (B) DIP–STR results of the mixed stain A, 1μl diluted 1/20 DNA was amplified with S-DIP and STR primers (left panel) and 2μl of DNA with L-DIP and STR primers (right panel). This last shows the positive amplification of the minor DNA component of the mixture which matches one of the suspects. Forensic Science International: Genetics Supplement Series 2011 3, e1-e2DOI: (10.1016/j.fsigss.2011.08.065) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions