F. Fu, X. Chen, Y. Feng, Y. Shen, Z. Feng, B. Bein

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Propofol EC50 for inducing loss of consciousness is lower in the luteal phase of the menstrual cycle F. Fu, X. Chen, Y. Feng, Y. Shen, Z. Feng, B. Bein British Journal of Anaesthesia Volume 112, Issue 3, Pages 506-513 (March 2014) DOI: 10.1093/bja/aet383 Copyright © 2014 The Author(s) Terms and Conditions

Fig 1 Individual responses to propofol at corresponding effect-concentrations (Ceprop). Unfilled squares represent ineffective responses to the corresponding Ceprop for achieving LOC. Filled squares represent effective responses to the corresponding Ceprop for achieving LOC. Arrows represent the midpoint Ceprop when crossing ineffective to effective response for LOC. The average Ceprop of crossing is represented by the horizontal dashed line. Ceprop, effect-site concentration of propofol. British Journal of Anaesthesia 2014 112, 506-513DOI: (10.1093/bja/aet383) Copyright © 2014 The Author(s) Terms and Conditions

Fig 2 Correlation analysis between the effect-site concentration of propofol (Ceprop) values at LOC and the level of female sex hormones (LH; FSH, oestrogen, progesterone). British Journal of Anaesthesia 2014 112, 506-513DOI: (10.1093/bja/aet383) Copyright © 2014 The Author(s) Terms and Conditions

Fig 3 Cumulative percentages of patients remaining unconscious after discontinuation of propofol and remifentanil infusion in the follicular group (unfilled circle and dotted line, empty area) and in the luteal group (filled circle and solid line, shaded area), obtained using the Kaplan–Meier survival analysis. Log-rank differences between the two groups were significant (P<0.01). British Journal of Anaesthesia 2014 112, 506-513DOI: (10.1093/bja/aet383) Copyright © 2014 The Author(s) Terms and Conditions