Long-Term Use of Aspirin and the Risk of Gastrointestinal Bleeding

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Long-Term Use of Aspirin and the Risk of Gastrointestinal Bleeding Edward S. Huang, MD, MPH, Lisa L. Strate, MD, MPH, Wendy W. Ho, MD, MPH, Salina S. Lee, MD, Andrew T. Chan, MD, MPH The American Journal of Medicine Volume 124, Issue 5, Pages 426-433 (May 2011) DOI: 10.1016/j.amjmed.2010.12.022 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure Multivariate-adjusted stratified analyses of gastrointestinal bleeding risk according to aspirin use. Multivariate hazard ratios are adjusted for age (years), nonsteroidal anti-inflammatory drug use (yes or no), smoking status (never, past, current), body mass index (<21, 21-22.9, 23-24.9, 25-29.9, ≥30 kg/m2), physical activity (<1.7, 1.7-4.5, 4.6-10.5, 10.6-22.0, ≥22.1 mets/wk), and alcohol (0, 0.1-4.9, 5-14, ≥15 g/d). For each stratified analysis, the stratification variable was omitted from the model. GI=gastrointestinal; NSAID=nonsteroidal anti-inflammatory drug. The American Journal of Medicine 2011 124, 426-433DOI: (10.1016/j.amjmed.2010.12.022) Copyright © 2011 Elsevier Inc. Terms and Conditions