Algorithm showing practical approach to persistent pulmonary hypertension of the newborn (PPHN) based on oxygenation, systemic blood pressure, and cardiac.

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Algorithm showing practical approach to persistent pulmonary hypertension of the newborn (PPHN) based on oxygenation, systemic blood pressure, and cardiac function. Algorithm showing practical approach to persistent pulmonary hypertension of the newborn (PPHN) based on oxygenation, systemic blood pressure, and cardiac function. See text for details.ECMO=extracorporeal membrane oxygenation; IV=intravenous; LR=lactated ringers solution; NO=nitric oxide; OI=oxygenation index; Paw=mean airway pressure; PEEP=positive end-expiratory pressure; PGE1=prostaglandin E1; PGI2=prostaglandin I2; PO-OG=per oral or orogastric. Copyright Satyan Lakshminrusimha. Satyan Lakshminrusimha, and Martin Keszler Neoreviews 2015;16:e680-e692 ©2015 by American Academy of Pediatrics