Neuroimaging: Perception at the Brain's Core

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Neuroimaging: Perception at the Brain's Core David A. Leopold, Alexander Maier  Current Biology  Volume 16, Issue 3, Pages R95-R98 (February 2006) DOI: 10.1016/j.cub.2006.01.026 Copyright © 2006 Elsevier Ltd Terms and Conditions

Figure 1 Core brain structures that may be involved in percept generation. (A) In Descartes' theory, perception arises when a sensory pattern is transmitted to the soul via the pineal gland (glandula H, pink). (B) Using functional magnetic resonance imaging (fMRI), two recent studies [5,6] found that activity in the lateral geniculate nucleus of the thalamus (green) correlated strongly with internally generated subjective perceptual changes during binocular rivalry. Current Biology 2006 16, R95-R98DOI: (10.1016/j.cub.2006.01.026) Copyright © 2006 Elsevier Ltd Terms and Conditions

Figure 2 Binocular rivalry in the LGN as measured with fMRI. (A) Information from the two eyes remains segregated in its projections to the LGN (red and green layers). While LGN then projects to the neocortex, it receives numerous direct and indirect projections back from the cortex, which are likely to shape the perceptual modulations observed in the present study. (B) Cartoon of stimulus, percept, and fMRI activity in a biased voxel during binocular rivalry (top) and sequential monocular switching (control condition, bottom). Note that the similar activity pattern in the two conditions reflects the similar percepts, rather than the very different inputs. Current Biology 2006 16, R95-R98DOI: (10.1016/j.cub.2006.01.026) Copyright © 2006 Elsevier Ltd Terms and Conditions