Perioperative administration of fibrinogen does not increase adverse cardiac and thromboembolic events after cardiac surgery J. Fassl, G. Lurati Buse,

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Presentation transcript:

Perioperative administration of fibrinogen does not increase adverse cardiac and thromboembolic events after cardiac surgery J. Fassl, G. Lurati Buse, M. Filipovic, O. Reuthebuch, K. Hampl, M.D. Seeberger, D. Bolliger British Journal of Anaesthesia Volume 114, Issue 2, Pages 225-234 (February 2015) DOI: 10.1093/bja/aeu364 Copyright © 2015 The Author(s) Terms and Conditions

Fig 1 Flow chart of inclusion and exclusion. PS, propensity score. British Journal of Anaesthesia 2015 114, 225-234DOI: (10.1093/bja/aeu364) Copyright © 2015 The Author(s) Terms and Conditions

Fig 2 Perioperative fibrinogen concentrations in cases with fibrinogen administration and PS-matched controls without fibrinogen administration before surgery (Preop), directly after surgery (Postop), and in the morning of the first (Day 1) and second day (Day 2) after surgery. No significant difference in perioperative fibrinogen concentrations between the two groups were found (P=0.815). British Journal of Anaesthesia 2015 114, 225-234DOI: (10.1093/bja/aeu364) Copyright © 2015 The Author(s) Terms and Conditions

Fig 3 Kaplan–Meier survival curves for combined endpoint (a) and mortality (b). Probability of mortality, thromboembolic event, or both in patients with and without perioperative fibrinogen administration. Data are HR and their 95% confidence interval. P-values were derived from log-rank test. British Journal of Anaesthesia 2015 114, 225-234DOI: (10.1093/bja/aeu364) Copyright © 2015 The Author(s) Terms and Conditions