Digestive Tract Esophagus (No.2) Stomach (No.25) Small intestine (N0.1) Large intestine (No.26) Jun Zhou School of Medicine, Zhejiang University

Mucosa Submucosa Muscularis externa Adventitia Esophagus (No.2)

Mucosa Epi. Submucosa Muscularis externa Lamina propria Muscularis mucosae Submucosa LCT Mucus-secreting glands Muscularis externa

Mucosa Epi. Lamina propria Muscularis mucosae

Mucus –secreting glands in the submucosa Muscularis mucosae ducts Mucus-secreting glands Mucus –secreting glands in the submucosa

Esophagus: adventitia Muscularis externa Esophagus: adventitia

Mucosa Submucosa Muscularis externa Stomach (No.25) Serosa

Mucosa of stomach Epithelium (mucus secreting cells) Parietal cell Lamina propria Chief cell Muscularis mucosae Mucosa of stomach

Mucosa Epithelium Mucus secreting cells Lamina propria CT, Gastric gland Muscularis mucosae Stomach

Parietal cells In the neck and body of the glands Column or pyramidal Eosinophilic cytoplasm Parietal cells

Chief cells In the body and base of the glands Columnar Basophilic cytoplasm Chief cells

Muscularis externa Myenteric plexus

Small intestine Mucosa epi. lamina propria muscularis mucosa Submucosa Muscularis externa Serosa Luminal surface modification: 1.Plicae circulares 2.Intestinal villi 3.Microvilli

Mucosa Submucosa Muscularis externa Serosa Human jejunum

Villus Epithelium 1.absorptive cell striated border (microvilli) 2.Goblet cell Lamina propria CT+SM

Intestinal glands Columnar cells Goblet cells Paneth cells at the base of the crypts 3-5 in a group Acidophilic G.

Muscularis externa Myenteric plexus

Serosa CT Mesothelium

Large intestine Small intestine

No villi No Paneth cell Numerous Goblet cells

Large intestine: Muscularis externa with myenteric plexus

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