Erratum to “Molecular mechanisms of irbesartan suppressing atherosclerosis in high cholesterol-diet apolipoprotein E knock-out mice” [Int J Cardiol 139.

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Erratum to “Molecular mechanisms of irbesartan suppressing atherosclerosis in high cholesterol-diet apolipoprotein E knock-out mice” [Int J Cardiol 139 (2010) 113–22] Rui Yao, Xiang Cheng, Yong Chen, Jiang-Jiao Xie, Xian Yu, Meng-Yang Liao, Ying-Jun Ding, Ting-Ting Tang, Yu-Hua Liao International Journal of Cardiology Volume 177, Issue 3, Pages 1146-1148 (December 2014) DOI: 10.1016/j.ijcard.2014.08.120 Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 A. Atherosclerotic lesion in ApoE KO mice. a–c, the whole aorta stained with oil red O. d–f, cross-sectional section stained with hematoxylin–eosin. Magnification ×100. g–i: Cryostat section of aortic root stained with oil red O. Magnification ×40. a, d, g: ND group; b, e, h: HCD group; c, f, i: HCD+Irb group. B. Atherosclerotic lesion area in aortic root [B (1)] and the percentage of the lesion area/lumina [B (2)]. Each bar represents mean±SEM (n=8 per group). Irb, irbesartan 10mgkg−1 d−1. *P<0.01 vs. the ND group; #P<0.01 vs. the HCD group. International Journal of Cardiology 2014 177, 1146-1148DOI: (10.1016/j.ijcard.2014.08.120) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Expression of Rac and p47phox in the atherosclerotic aorta of ApoE KO mice. A: The mRNA levels of Rac and p47phox were assayed by quantitative real-time reverse-transcription polymerase chain reaction. Each bar represents mean±SEM (n=6 per group). B: The protein levels of p47phox in membrane extract and Rac-GTP were measured by western blots. B (1): The representative results of western blots of p47phox and Rac-GTP are shown. B (2): Densitometric measurements of p47phox and Rac-GTP from western blots. Each bar represents mean±SEM (n=3). Irb, irbesartan 10mgkg−1 d−1. *P<0.01 vs. the ND group; #P<0.01 vs. the HCD group. International Journal of Cardiology 2014 177, 1146-1148DOI: (10.1016/j.ijcard.2014.08.120) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Expression of TNF-α, IL-6, MCP-1 and VCAM-1 in the atherosclerotic aorta of ApoE KO mice. A: The mRNA levels for TNF-α, IL-6, MCP-1 and VCAM-1 were assayed by quantitative real-time reverse transcription polymerase chain reaction. Each bar represents mean±SEM (n=6 per group). B: The protein levels of TNF-α, IL-6, MCP-1 and VCAM-1 were measured by western blots. B (1): The representative results of western blots of TNF-α, IL-6, MCP-1 and VCAM-1 are shown. B (2): Densitometric measurements of TNF-α, IL-6, MCP-1 and VCAM-1 from western blots. Each bar represents mean±SEM (n=3). Irb, irbesartan 10 mg kg−1 d−1. *P<0.01 vs. the ND group; #P<0.01 vs. the HCD group; +P<0.05 vs. the ND group. International Journal of Cardiology 2014 177, 1146-1148DOI: (10.1016/j.ijcard.2014.08.120) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions