Demonstration of persistent tumor cells 4 weeks after radiofrequency ablation of a pulmonary adenocarcinoma Stéphane Renaud, Marco Schiavon, MD, Nicola.

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Demonstration of persistent tumor cells 4 weeks after radiofrequency ablation of a pulmonary adenocarcinoma Stéphane Renaud, Marco Schiavon, MD, Nicola Santelmo, MD, Gilbert Massard, MD, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 144, Issue 5, Pages e111-e113 (November 2012) DOI: 10.1016/j.jtcvs.2012.07.028 Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Computed tomography scans taken before, during, and after the treatment. A, Supine chest computed tomography scan performed before radiofrequency treatment showing lesion located in left upper lobe. B, Prone computed tomography scan during radiofrequency treatment with correct insertion of the probe in the lesion. C, Prone computed tomography scan after procedure showing a successful radiological procedure and a pneumothorax. The Journal of Thoracic and Cardiovascular Surgery 2012 144, e111-e113DOI: (10.1016/j.jtcvs.2012.07.028) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 A, Intraoperative view of the lesion after wedge resection. B and C, Pathologic examination of the specimen marked with hematoxylin & eosin stain confirming the presence of adenocarcinoma with suspected multiple proliferating cells. D, Immunohistochemical analysis using anti-Ki67 antibody confirming the presence of major foci of viable neoplastic cells (black arrow) representing >40% of the tumor. The Journal of Thoracic and Cardiovascular Surgery 2012 144, e111-e113DOI: (10.1016/j.jtcvs.2012.07.028) Copyright © 2012 The American Association for Thoracic Surgery Terms and Conditions