Similar Outcomes of Cryopreserved Allogeneic Peripheral Stem Cell Transplants (PBSCT) Compared to Fresh Allografts Dong Hwan Kim, Nazir Jamal, Ronnie.

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Similar Outcomes of Cryopreserved Allogeneic Peripheral Stem Cell Transplants (PBSCT) Compared to Fresh Allografts Dong Hwan Kim, Nazir Jamal, Ronnie Saragosa, David Loach, Janice Wright, Vikas Gupta, John Kuruvilla, Jeffrey H. Lipton, Mark Minden, Hans A. Messner Biology of Blood and Marrow Transplantation Volume 13, Issue 10, Pages 1233-1243 (October 2007) DOI: 10.1016/j.bbmt.2007.07.003 Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Engraftment kinetics of neutrophils (A), platelets (B), and lymphocytes (C) after cryopreserved and fresh PBSCT. D, Shows similar serial recoveries of lymphocyte counts after cryopreserved and fresh PBSCT. Biology of Blood and Marrow Transplantation 2007 13, 1233-1243DOI: (10.1016/j.bbmt.2007.07.003) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Incidence of acute (A) and cGVHD (B) after cryopreserved and fresh PBSCT. Biology of Blood and Marrow Transplantation 2007 13, 1233-1243DOI: (10.1016/j.bbmt.2007.07.003) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Overall survival, nonrelapse mortality, and recurrence rates of patients receiving cryopreserved or freshly procured allografts. Biology of Blood and Marrow Transplantation 2007 13, 1233-1243DOI: (10.1016/j.bbmt.2007.07.003) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 4 Frequency of clonogenic hematopoietic progenitors in PBSC preparation before cryopreservation and after thawing. Colony counts after 14 days’ incubation of 5 × 104 TNCs. Abbreviations: CFU-GM, colony-forming units granulocyte-macrophage; BFU-E, Burst-forming units erythroid; CFU-MEG, colony-forming units megakaryocyte; CFU-GEMM, colony-forming units granulocyte-erythrocyte-monocyte-megakaryocyte. Biology of Blood and Marrow Transplantation 2007 13, 1233-1243DOI: (10.1016/j.bbmt.2007.07.003) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions