Curbing Tregs’ (Lack of) Enthusiasm

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Curbing Tregs’ (Lack of) Enthusiasm Taha Merghoub, Jedd D. Wolchok Cell Volume 169, Issue 6, Pages 981-982 (June 2017) DOI: 10.1016/j.cell.2017.05.027 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 1 Impact of NRP1-Deficient Tregs on WT Tregs WT Tregs are suppressive, and Nrp1−/− Tregs lose their suppressive ability while maintaining Foxp3 expression. When Nrp1−/− Tregs are in the presence of WT Tregs, they impact their suppressive function. The crosstalk between these two types of Tregs is interferon gamma dependent. Cell 2017 169, 981-982DOI: (10.1016/j.cell.2017.05.027) Copyright © 2017 Elsevier Inc. Terms and Conditions