Aortic Valve Replacement for Patients With Severe Aortic Stenosis: Risk Factors and Their Impact on 30-Month Mortality Edward L. Hannan, PhD, Zaza Samadashvili,

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Presentation transcript:

Aortic Valve Replacement for Patients With Severe Aortic Stenosis: Risk Factors and Their Impact on 30-Month Mortality Edward L. Hannan, PhD, Zaza Samadashvili, MD, Stephen J. Lahey, MD, Craig R. Smith, MD, Alfred T. Culliford, MD, Robert S.D. Higgins, MD, Jeffrey P. Gold, MD, Robert H. Jones, MD The Annals of Thoracic Surgery Volume 87, Issue 6, Pages 1741-1749 (June 2009) DOI: 10.1016/j.athoracsur.2009.02.058 Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Survival after isolated aortic valve replacement versus aortic valve replacement with concomitant coronary artery bypass grafting. Dashed lines are survival for age- and sex-matched US population. Solid and dash-dotted lines represent survival for aortic valve replacement patients with and without concomitant coronary artery bypass grafting, respectively. (A) Unadjusted Kaplan-Meier survival curves. (B) Adjusted Kaplan-Meier survival curves. The Annals of Thoracic Surgery 2009 87, 1741-1749DOI: (10.1016/j.athoracsur.2009.02.058) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Survival after aortic valve replacement according to patient age. Dashed lines are survival for age- and sex-matched US population. Solid lines represent risk-adjusted survival in selected age and surgery subgroups. (A) Nonelderly patients (age < 75 years) with isolated aortic valve replacement. (B) Elderly patients (age > 75 years) with isolated aortic valve replacement. (C) Nonelderly patients undergoing aortic valve replacement with coronary artery bypass graft surgery. (D) Elderly patients undergoing aortic valve replacement with coronary artery bypass graft surgery. The Annals of Thoracic Surgery 2009 87, 1741-1749DOI: (10.1016/j.athoracsur.2009.02.058) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Survival after isolated aortic valve replacement according to preoperative cardiac risk factors. Dashed lines are survival for age- and sex-matched US population. Solid and dash-dotted lines represent risk-adjusted survival for patients with and without each risk factor, respectively. (A) Acute myocardial infarction less than 24 hours or hemodynamically unstable. (B) Congestive heart failure. (C) Left ventricular ejection fraction less than 0.40. (D) Combination of congestive heart failure, left ventricular ejection fraction less than 0.40, and acute myocardial infarction less than 24 hours or hemodynamically unstable. The Annals of Thoracic Surgery 2009 87, 1741-1749DOI: (10.1016/j.athoracsur.2009.02.058) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Survival after aortic valve replacement with concomitant coronary artery bypass graft surgery according to preoperative cardiac risk factors. Dashed lines are survival for age- and sex-matched US population. Solid and dash-dotted lines represent risk-adjusted survival for patients with and without each risk factor, respectively. (A) Acute myocardial infarction less than 24 hours or hemodynamically unstable. (B) Congestive heart failure. (C) Left ventricular ejection fraction less than 0.40. (D) Combination of congestive heart failure, left ventricular ejection fraction less than 0.40, and acute myocardial infarction less than 24 hours or hemodynamically unstable. The Annals of Thoracic Surgery 2009 87, 1741-1749DOI: (10.1016/j.athoracsur.2009.02.058) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions