Toll-like receptor 2–positive and Toll-like receptor 4–positive cells in adenoids of children exposed to passive smoking Antonio Ricci, MD, M. Antonietta.

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Presentation transcript:

Toll-like receptor 2–positive and Toll-like receptor 4–positive cells in adenoids of children exposed to passive smoking Antonio Ricci, MD, M. Antonietta Avanzini, PhD, Cristina Scaramuzza, MD, Anna Maria Castellazzi, PhD, Massimo Marconi, PhD, Gian Luigi Marseglia, MD Journal of Allergy and Clinical Immunology Volume 115, Issue 3, Pages 631-632 (March 2005) DOI: 10.1016/j.jaci.2004.11.044 Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 1 Phenotypic analysis of adenoidal T cells. In the left panel, lymphocytes are gated for forward and side scatter (R1). In the middle panel, cells are gated for CD8 positiveness (R2) after activation of R1 gate. In the right panel, TRL4+CD8 cells are reported after activation of R3=R1 and R2; quadrant markers are defined on appropriate isotype-matched control. All cells in the upper right quadrant were considered TRL4+CD8+. FSC-H, Forward scatter; SSC-H, side scatter; FL, fluorescence. Journal of Allergy and Clinical Immunology 2005 115, 631-632DOI: (10.1016/j.jaci.2004.11.044) Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

Fig 2 Percentage of TLR4+CD8+ cells in adenoids of children exposed to parental smoke compared with children not exposed. Medians are reported as horizontal lines. The statistical test used is the Mann-Whitney U test; P=.009. Journal of Allergy and Clinical Immunology 2005 115, 631-632DOI: (10.1016/j.jaci.2004.11.044) Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions