Mohamed A.M Hassan, M.Sc., Stephen R Killick, M.D. 

Slides:



Advertisements
Similar presentations
BMI and risk of dementia in two million people over two decades: a retrospective cohort study  Dr Nawab Qizilbash, MRCP, John Gregson, PhD, Michelle E.
Advertisements

Janet E. Robinson, F. I. B. S. , Melanie Wakelin, C. Stat. , Jayne E
Clinically significant and sustained weight loss is achievable in obese women with polycystic ovary syndrome followed in a regular medical practice  Lysanne.
Demián Glujovsky, M.D., M.Sc., Cynthia Farquhar, M.D., M.P.H. 
Male infertility: a biomarker of individual and familial cancer risk
Longitudinal depressive symptoms and state anxiety among women using assisted reproductive technology  Anjel Vahratian, Ph.D., M.P.H., Yolanda R. Smith,
Does Previous Salpingectomy Improve Implantation and Pregnancy Rates in Patients with Severe Tubal Factor Infertility who are Undergoing In Vitro Fertilization?
Janet E. Robinson, F. I. B. S. , Melanie Wakelin, C. Stat. , Jayne E
Long-term risk of ectopic pregnancy varies by method of tubal sterilization: a whole- population study  Eva Malacova, Ph.D., Anna Kemp, Ph.D., Roger Hart,
Measurement of inhibin A and inhibin pro-αC in early human pregnancy and their role in the prediction of pregnancy outcome in patients with recurrent.
Mike Ripley, M. D. , F. R. C. S. C. , Andrea Lanes, M. Sc
Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and in vitro fertilization success  Luke Simon,
Dennis J. Hand, Ph. D. , Vanessa L. Short, Ph. D. , M. P. H. , Diane J
Racial differences in fibroid prevalence and ultrasound findings in asymptomatic young women (18–30 years old): a pilot study  Erica E. Marsh, M.D., M.S.C.I.,
Changes in Smoking During Pregnancy in Ontario, 1995 to 2010: Results From the Canadian Community Health Survey  Hilary K. Brown, MSc, Piotr Wilk, PhD 
Differences in in vitro fertilization (IVF) outcome between white and black women in an inner-city, university-based IVF program  Fady I Sharara, M.D.,
Day 4 Estradiol Levels Predict Pregnancy Success in Women Undergoing Controlled Ovarian Hyperstimulation for IVF  John Y Phelps, M.D., Adam S Levine,
Temporal trends in clomiphene citrate use: a population-based study
Dramatic declines in implantation and pregnancy rates in patients who undergo repeated cycles of in vitro fertilization with blastocyst transfer after.
Mohamed A.M Hassan, M.Sc., Stephen R Killick, M.D. 
How old is too old? Challenges faced by clinicians concerning age cutoffs for patients undergoing in vitro fertilization  Robert L. Klitzman, M.D.  Fertility.
Effectiveness of combined tamoxifen citrate and testosterone undecanoate treatment in men with idiopathic oligozoospermia  Dimitrios A Adamopoulos, M.D.,
Assisted reproductive technology in the United States: 1999 results generated from the American Society for reproductive medicine/society for assisted.
Alka Prakash, M. D. , Susan Laird, Ph. D. , Elizabeth Tuckerman, M. Sc
Mieke Carine Wim Eeckhaut, Ph.D.  Fertility and Sterility 
Optimal timing for elective egg freezing
Success of intrauterine insemination in women aged 40–42 years
When do involuntarily infertile couples choose to seek medical help?
Lifestyle and pregnancy loss in a contemporary cohort of women recruited before conception: The LIFE Study  Germaine M. Buck Louis, Ph.D., M.S., Katherine.
Increased risk of pregnancy-induced hypertension and operative delivery after conception induced by in vitro fertilization/intracytoplasmic sperm injection.
Menstrual cycle length is an age-independent marker of female fertility: results from 6271 treatment cycles of in vitro fertilization  Thomas Brodin,
Mark D Hornstein, M. D. , Owen K Davis, M. D. , Joe B Massey, M. D
Epidemiology of male and female reproductive disorders and impact on fertility regulation and population growth  Kurt T. Barnhart, M.D., M.S.C.E.  Fertility.
From partner's desk to iPad
Male infertility: a biomarker of individual and familial cancer risk
Interaction of apolipoprotein E gene polymorphisms on miscarriage risk in black and white American women  Silvia Gamundi-Segura, M.Sc., Elena Torres-Perez,
Venous thromboembolism in relation to in vitro fertilization: an approach to determining the incidence and increase in risk in successful cycles  Karin.
Maximizing Pregnancy Rates and Limiting Higher-Order Multiple Conceptions by Determining the Optimal Number of Embryos to Transfer Based on Quality  Yunxia.
Paolo Vercellini, M. D. , Silvia Maddalena, M. D. , Olga De Giorgi, M
Frequency and effect of vaginal bleeding on pregnancy outcome during the first 3 weeks after positive β-hCG test results following IVF-ET  Glen E Hofmann,
Birth outcomes after spontaneous or assisted conception among infertile Australian women aged 28 to 36 years: a prospective, population-based study  Danielle.
“Information-rich” reproductive outcomes in carriers of a structural chromosome rearrangement ascertained on the basis of recurrent pregnancy loss  Michelle.
Relationship between serum leptin concentrations and bone mineral density as well as biochemical markers of bone turnover in women with postmenopausal.
Rhoda Wilson, Ph. D. , Marjorie A Maclean, M. D
Obesity does not impact implantation rates or pregnancy outcome in women attempting conception through oocyte donation  Allison Styne-Gross, M.D., Karen.
Ectopic pregnancy after transmyometrial embryo transfer: case report
Outcomes of spontaneous and assisted pregnancies in Turner syndrome: the U.S. National Institutes of Health experience  Tracy N. Hadnott, B.A., Harley.
Regulation of assisted reproductive technologies in the United States
Guido Ragni, M. D. , Mariangela Arnoldi, M. D. , Edgardo Somigliana, M
Cameron Gilbert, M. Sc. , Maria Valois, M. D. , FRCPC, Ph. D
Effect of endometriosis on in vitro fertilization
Brian W. Whitcomb, Ph. D. , Enrique F. Schisterman, Ph. D. , Mark A
Association of vitamin D intake and serum levels with fertility: results from the Lifestyle and Fertility Study  June L. Fung, Ph.D., Terryl J. Hartman,
Fertility and Sterility
Relationship between maternal age and aneuploidy in in vitro fertilization pregnancy loss  Steven D Spandorfer, M.D., Owen K Davis, M.D., Larry I Barmat,
Impact of subclinical hypothyroidism in women with recurrent early pregnancy loss  Lia A. Bernardi, M.D., Ronald N. Cohen, M.D., Mary D. Stephenson, M.D.,
Geoffrey M.H. Waites, Sc.D.  Fertility and Sterility 
High singleton live birth rate confirmed after ovulation induction in women with anovulatory polycystic ovary syndrome: validation of a prediction model.
Tubal sterilization trends in the United States
Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study  Xiaobin Wang, M.D., Changzhong Chen, M.D., Lihua.
Egg production predicts a doubling of in vitro fertilization pregnancy rates even within defined age and ovarian reserve categories  Melissa C. Yih, M.D.,
Familial oligoasthenoteratozoospermia: evidence of autosomal dominant inheritance with sex-limited expression  Joep H.A.M. Tuerlings, M.D., Ph.D., Ron.
Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium.
Fertility after discontinuation of treatment with an oral contraceptive containing 30 μg of ethinyl estradiol and 2 mg of dienogest  Inka Wiegratz, Ph.D.,
Early pregnancy loss in in vitro fertilization (IVF) is a positive predictor of subsequent IVF success  G.Wright Bates, M.D., Elizabeth S Ginsburg, M.D. 
Male biological clock: a critical analysis of advanced paternal age
Platelet-activating factor significantly enhances intrauterine insemination pregnancy rates in non-male factor infertility  William E Roudebush, Ph.D.,
Stephen J Winters, M. D. , Evelyn Talbott, David S Guzick, Ph. D. , M
The cumulative probability of liveborn multiples after in vitro fertilization: a cohort study of more than 10,000 women  Beth A. Malizia, M.D., Laura.
Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles  John L. Frattarelli,
Presentation transcript:

Effect of male age on fertility: evidence for the decline in male fertility with increasing age  Mohamed A.M Hassan, M.Sc., Stephen R Killick, M.D.  Fertility and Sterility  Volume 79, Pages 1520-1527 (June 2003) DOI: 10.1016/S0015-0282(03)00366-2

FIGURE 1 The effect of increasing age, presented as age groups in years, on fecundity expressed as time to pregnancy (TTP) in months. Women’s age effect on TTP was calculated using the (A) age at conception and (B) the age at the onset of attempting to achieve pregnancy. Men’s age effect on TTP was calculated using (C) the age at conception and (D) the age at the onset of attempting to achieve pregnancy. Values in each figure represent the mean TTP for the age groups; the error bars represent the standard error of the mean. (P<.001 for all calculations.) Hassan. Effect of male age on fertility. Fertil Steril 2003. Fertility and Sterility 2003 79, 1520-1527DOI: (10.1016/S0015-0282(03)00366-2)

FIGURE 2 The effect of increasing age among women and men in a pregnant population on the cumulative conception rates during the first year of attempting to achieve pregnancy. (A) For women, the cumulative conception rates for each age group are as follows: <20 years old (▵), 20 to 34 years old (•), 35 to 39 years old (□), and ≥40 years old (▴). (B) For men, the cumulative conception rates for each age group are as follows: <20 years old (▵), 20 to 39 years old (•), 40 to 49 years old (□), ≥50 years old (▴). (P<.001 for both calculations.) Hassan. Effect of male age on fertility. Fertil Steril 2003. Fertility and Sterility 2003 79, 1520-1527DOI: (10.1016/S0015-0282(03)00366-2)