Volume 11, Issue 3, Pages (March 2010)

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Volume 11, Issue 3, Pages 231-240 (March 2010) Comparison of patient-reported breast, arm, and shoulder symptoms and body image after radiotherapy for early breast cancer: 5-year follow-up in the randomised Standardisation of Breast Radiotherapy (START) trials Dr Penelope Hopwood, MD, Joanne S Haviland, MSc, Georges Sumo, MSc, Judith Mills, MPhil, Prof Judith M Bliss, MSc, Prof John R Yarnold, FRCR The Lancet Oncology Volume 11, Issue 3, Pages 231-240 (March 2010) DOI: 10.1016/S1470-2045(09)70382-1 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 Trial profiles of patients from START trial A (A) and trial B (B) quality-of-life study The Lancet Oncology 2010 11, 231-240DOI: (10.1016/S1470-2045(09)70382-1) Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 2 Forest plots of normal tissue effects assessed as moderate or marked by patients, according to radiotherapy regimen Positions of squares in the forest plot show the estimate of the hazard ratio describing relative effect of the test schedule compared with control, with the 95% CI represented by horizontal lines. Squares to the left of the vertical line indicate when rates of adverse effects are lower in the test schedule compared with control; estimates to the right of the line indicate whether rates are higher in the test schedule. Size of squares is proportional to the precision of the estimate, with larger squares indicating greater precision. *In patients who had completed breast-conserving surgery only. (A) START trial A, 41·6 Gy vs 50 Gy. (B) START trial A, 39 Gy vs 50 Gy. (C) START Trial B, 40 Gy vs 50 Gy. The Lancet Oncology 2010 11, 231-240DOI: (10.1016/S1470-2045(09)70382-1) Copyright © 2010 Elsevier Ltd Terms and Conditions