Inherited Cardiomyopathies

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Presentation transcript:

Inherited Cardiomyopathies Polakit Teekakirikul, Melissa A. Kelly, Heidi L. Rehm, Neal K. Lakdawala, Birgit H. Funke The Journal of Molecular Diagnostics Volume 15, Issue 2, Pages 158-170 (March 2013) DOI: 10.1016/j.jmoldx.2012.09.002 Copyright © 2013 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

Figure 1 Cellular locations of proteins involved in inherited cardiomyopathies. Structural components of the myocyte that are impacted by cardiomyopathy include the sarcomere, Z-disk, nuclear lamina proteins, intermediate filaments, the desmosome, and the dystrophin-associated glycoprotein complex. Genes linked to cardiomyopathy and the locations of their protein products are indicated. Adapted with permission from the American Society for Clinical Investigation.33 The Journal of Molecular Diagnostics 2013 15, 158-170DOI: (10.1016/j.jmoldx.2012.09.002) Copyright © 2013 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions