Patient 14. Patient 14. Secondary progressive MS. Axial contrast-enhanced T1-weighted MR image (600/27/1 [TR/TE/excitation]). A, No enhanced lesion can.

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Patient 14. Patient 14. Secondary progressive MS. Axial contrast-enhanced T1-weighted MR image (600/27/1 [TR/TE/excitation]). A, No enhanced lesion can be seen on image 6 months prior to follow-up.B, A new, nodular, enhanced MS lesion appears 6 months later.C, After 6 months, the pattern of nodular enhancement converts to a ringlike pattern.D, After another 6 months, the ringlike, enhanced lesion cannot be seen. Juan He et al. AJNR Am J Neuroradiol 2001;22:664-669 ©2001 by American Society of Neuroradiology