Bud Building by Septin Patch Hole Punching

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Bud Building by Septin Patch Hole Punching Fabrice Caudron, Yves Barral Developmental Cell Volume 26, Issue 2, Pages 115-116 (July 2013) DOI: 10.1016/j.devcel.2013.07.004 Copyright © 2013 Elsevier Inc. Terms and Conditions

Figure 1 A Mechanism for the Recruitment and Ring Formation of Septins at the Polarity Site A single patch of active Cdc42 forms at the plasma membrane (1), which in turn recruits a patch of septins (2). Exocytic vesicles coated with active Cdc42 are targeted to this area (3) and dilute out septins from the inside of the patch (4 to 6). Septins then form a ring encircling the Cdc42 patch (7). Developmental Cell 2013 26, 115-116DOI: (10.1016/j.devcel.2013.07.004) Copyright © 2013 Elsevier Inc. Terms and Conditions