Amino Acid Signaling to TOR Activation: Vam6 Functioning as a Gtr1 GEF

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Amino Acid Signaling to TOR Activation: Vam6 Functioning as a Gtr1 GEF Li Li, Kun-Liang Guan Molecular Cell Volume 35, Issue 5, Pages 543-545 (September 2009) DOI: 10.1016/j.molcel.2009.08.010 Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 1 Functions of Vam6 and Rag GTPases in TORC1 Activation by Amino Acids Corresponding genes in S. cerevisiae and human are shown in the same color. Dashed lines denote an indirect connection, whereas solid arrows indicate a direct effect. Because whether Vam6 stimulates Gtr2 nucleotide exchange is unknown, the guanine nucleotides in Gtr2 and RagC/D are not shown in order to avoid potential confusion. Molecular Cell 2009 35, 543-545DOI: (10.1016/j.molcel.2009.08.010) Copyright © 2009 Elsevier Inc. Terms and Conditions